Detalhe da pesquisa
1.
Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS.
PLoS Biol
; 18(6): e3000725, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32516343
2.
Humanized Transgenic Mice Are Resistant to Chronic Wasting Disease Prions From Norwegian Reindeer and Moose.
J Infect Dis
; 226(5): 933-937, 2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33502474
3.
A naturally occurring variant of the human prion protein completely prevents prion disease.
Nature
; 522(7557): 478-81, 2015 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26061765
4.
Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS.
PLoS Pathog
; 11(7): e1004953, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26135918
5.
A novel prion disease associated with diarrhea and autonomic neuropathy.
N Engl J Med
; 369(20): 1904-14, 2013 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24224623
6.
Prion-mediated neurodegeneration is associated with early impairment of the ubiquitin-proteasome system.
Acta Neuropathol
; 131(3): 411-25, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26646779
7.
N-terminal domain of prion protein directs its oligomeric association.
J Biol Chem
; 289(37): 25497-508, 2014 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25074940
8.
Inherited prion disease A117V is not simply a proteinopathy but produces prions transmissible to transgenic mice expressing homologous prion protein.
PLoS Pathog
; 9(9): e1003643, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24086135
9.
Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes.
EMBO J
; 29(1): 222-35, 2010 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19927122
10.
Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection.
PLoS Pathog
; 8(2): e1002538, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22359509
11.
Atypical scrapie prions from sheep and lack of disease in transgenic mice overexpressing human prion protein.
Emerg Infect Dis
; 19(11): 1731-9, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24188521
12.
Effect of fixation on brain and lymphoreticular vCJD prions and bioassay of key positive specimens from a retrospective vCJD prevalence study.
J Pathol
; 223(4): 511-8, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21294124
13.
Kuru prions and sporadic Creutzfeldt-Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice.
Proc Natl Acad Sci U S A
; 105(10): 3885-90, 2008 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-18316717
14.
Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein.
J Gen Virol
; 91(Pt 10): 2651-7, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20610667
15.
Generation of a panel of antibodies against proteins encoded on human chromosome 21.
J Negat Results Biomed
; 9: 7, 2010 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20727138
16.
First report of Creutzfeldt-Jakob disease occurring in 2 siblings unexplained by PRNP mutation.
J Neuropathol Exp Neurol
; 67(9): 838-41, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18716560
17.
Molecular diagnosis of human prion disease.
Methods Mol Biol
; 459: 197-227, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18576157
18.
Experimental sheep BSE prions generate the vCJD phenotype when serially passaged in transgenic mice expressing human prion protein.
J Neurol Sci
; 386: 4-11, 2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29406965
19.
Clinical presentation and pre-mortem diagnosis of variant Creutzfeldt-Jakob disease associated with blood transfusion: a case report.
Lancet
; 368(9552): 2061-7, 2006 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17161728
20.
Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein.
Brain
; 129(Pt 6): 1557-69, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16597650