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1.
Am J Public Health ; 104(4): 621-8, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23865656

RESUMO

Surges in demand for professional mental health services occasioned by disasters represent a major public health challenge. To build response capacity, numerous psychological first aid (PFA) training models for professional and lay audiences have been developed that, although often concurring on broad intervention aims, have not systematically addressed pedagogical elements necessary for optimal learning or teaching. We describe a competency-based model of PFA training developed under the auspices of the Centers for Disease Control and Prevention and the Association of Schools of Public Health. We explain the approach used for developing and refining the competency set and summarize the observable knowledge, skills, and attitudes underlying the 6 core competency domains. We discuss the strategies for model dissemination, validation, and adoption in professional and lay communities.


Assuntos
Educação Baseada em Competências/métodos , Desastres , Educação/métodos , Primeiros Socorros/psicologia , Modelos Educacionais , Consenso , Educação/organização & administração , Emergências/psicologia , Primeiros Socorros/métodos , Humanos , Autocuidado , Triagem/métodos
2.
Health Commun ; 29(6): 598-609, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-23799806

RESUMO

This study examines the attitudinal impact of an Extended Parallel Process Model (EPPM)-based training curriculum on local public health department (LHD) workers' willingness to respond to representative public health emergency scenarios. Data are from 71 U.S. LHDs in urban and rural settings across nine states. The study explores changes in response willingness and EPPM threat and efficacy appraisals between randomly assigned control versus intervention health departments, at baseline and 1 week post curriculum, through an EPPM-based survey/resurvey design. Levels of response willingness and emergency response-related attitudes/beliefs are measured. Analyses focus on two scenario categories that have appeared on a U.S. government list of scenarios of significant concern: a weather-related emergency and a radiological "dirty" bomb event (U.S. Department of Homeland Security, 2007). The greatest impact from the training intervention on response willingness was observed among LHD workers who had low levels of EPPM-related threat and efficacy perceptions at baseline. Self-efficacy and response efficacy and response willingness increased in intervention LHDs for both scenarios, with greater response willingness increases observed for the radiological "dirty" bomb terrorism scenario. Findings indicate the importance of building efficacy versus enhancing threat perceptions as a path toward greater response willingness, and suggest the potential applicability of such curricular interventions for boosting emergency response willingness among other cadres of health providers.


Assuntos
Emergências/psicologia , Comunicação em Saúde , Administração em Saúde Pública , Adulto , Atitude do Pessoal de Saúde , Coleta de Dados , Planejamento em Desastres/métodos , Desastres , Feminino , Comunicação em Saúde/métodos , Pessoal de Saúde/psicologia , Humanos , Masculino , Administração em Saúde Pública/educação , Administração em Saúde Pública/métodos , Medição de Risco , Autoeficácia , Terrorismo , Estados Unidos
3.
J Public Health Manag Pract ; 20 Suppl 5: S24-9, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25072485

RESUMO

INTRODUCTION: The Johns Hopkins Center for Public Health Preparedness, which houses the Centers for Disease Control and Prevention-funded Preparedness and Emergency Response Learning Center, has been addressing the challenge of disaster-caused behavioral health surge by conducting training programs in psychological first aid (PFA) for public health professionals. This report describes our approach, named RAPID-PFA, and summarizes training evaluation data to determine if relevant knowledge, skills, and attitudes are imparted to trainees to support effective PFA delivery. BACKGROUND/RATIONALE: In the wake of disasters, there is an increase in psychological distress and dysfunction among survivors and first responders. To meet the challenges posed by this surge, a professional workforce trained in PFA is imperative. METHODS/ACTIVITY: More than 1500 participants received a 1-day RAPID-PFA training. Pre-/postassessments were conducted to measure (a) required knowledge to apply PFA; (b) perceived self-efficacy, that is, belief in one's own ability, to apply PFA techniques; and (c) confidence in one's own resilience in a crisis context. Statistical techniques were used to validate the extent to which the survey successfully measured individual PFA constructs, that is, unidimensionality, and to quantify the reliability of the assessment tool. RESULTS/OUTCOME: Statistically significant pre-/postimprovements were observed in (a) knowledge items supportive of PFA delivery, (b) perceived self-efficacy to apply PFA interventions, and (c) confidence about being a resilient PFA provider. Cronbach alpha coefficients ranging from 0.87 to 0.90 suggested that the self-reported measures possessed sufficient internal consistency. DISCUSSION: Findings were consistent with our pilot work, and with our complementary research initiatives validating a variant of RAPID-PFA with faith communities. LESSONS LEARNED/NEXT STEPS: The RAPID-PFA model promises to be a broadly applicable approach to extending community behavioral health surge capacity. Relevant next steps include evaluating the effectiveness of trained providers in real crisis situations, and determining if PFA training may have potential beyond the disaster context.


Assuntos
Desastres , Socorristas/psicologia , Primeiros Socorros , Pessoal de Saúde/psicologia , Resiliência Psicológica , Humanos , Modelos Teóricos
4.
Prehosp Disaster Med ; 28(1): 8-15, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23174414

RESUMO

INTRODUCTION: Community disaster preparedness plans, particularly those with content that would mitigate the effects of psychological trauma on vulnerable rural populations, are often nonexistent or underdeveloped. The purpose of the study was to develop and evaluate a model of disaster mental health preparedness planning involving a partnership among three, key stakeholders in the public health system. METHODS: A one-group, post-test, quasi-experimental design was used to assess outcomes as a function of an intervention designated Guided Preparedness Planning (GPP). The setting was the eastern-, northern-, and mid-shore region of the state of Maryland. Partner participants were four local health departments (LHDs), 100 faith-based organizations (FBOs), and one academic health center (AHC)-the latter, collaborating entities of the Johns Hopkins University and the Johns Hopkins Health System. Individual participants were 178 community residents recruited from counties of the above-referenced geographic area. Effectiveness of GPP was based on post-intervention assessments of trainee knowledge, skills, and attitudes supportive of community disaster mental health planning. Inferences about the practicability (feasibility) of the model were drawn from pre-defined criteria for partner readiness, willingness, and ability to participate in the project. Additional aims of the study were to determine if LHD leaders would be willing and able to generate post-project strategies to perpetuate project-initiated government/faith planning alliances (sustainability), and to develop portable methods and materials to enhance model application and impact in other health jurisdictions (scalability). RESULTS: The majority (95%) of the 178 lay citizens receiving the GPP intervention and submitting complete evaluations reported that planning-supportive objectives had been achieved. Moreover, all criteria for inferring model feasibility, sustainability, and scalability were met. CONCLUSIONS: Within the span of a six-month period, LHDs, FBOs, and AHCs can work effectively to plan, implement, and evaluate what appears to be an effective, practical, and durable model of capacity building for public mental health emergency planning.


Assuntos
Serviços Comunitários de Saúde Mental/organização & administração , Planejamento em Desastres/organização & administração , Coalizão em Cuidados de Saúde/organização & administração , Fortalecimento Institucional/métodos , Serviços Comunitários de Saúde Mental/métodos , Relações Comunidade-Instituição , Planejamento em Desastres/métodos , Humanos , Maryland , Modelos Organizacionais , Saúde da População Rural , Estados Unidos
5.
BMC Public Health ; 12: 164, 2012 Mar 07.
Artigo em Inglês | MEDLINE | ID: mdl-22397547

RESUMO

BACKGROUND: The all-hazards willingness to respond (WTR) of local public health personnel is critical to emergency preparedness. This study applied a threat-and efficacy-centered framework to characterize these workers' scenario and jurisdictional response willingness patterns toward a range of naturally-occurring and terrorism-related emergency scenarios. METHODS: Eight geographically diverse local health department (LHD) clusters (four urban and four rural) across the U.S. were recruited and administered an online survey about response willingness and related attitudes/beliefs toward four different public health emergency scenarios between April 2009 and June 2010 (66% response rate). Responses were dichotomized and analyzed using generalized linear multilevel mixed model analyses that also account for within-cluster and within-LHD correlations. RESULTS: Comparisons of rural to urban LHD workers showed statistically significant odds ratios (ORs) for WTR context across scenarios ranging from 1.5 to 2.4. When employees over 40 years old were compared to their younger counterparts, the ORs of WTR ranged from 1.27 to 1.58, and when females were compared to males, the ORs of WTR ranged from 0.57 to 0.61. Across the eight clusters, the percentage of workers indicating they would be unwilling to respond regardless of severity ranged from 14-28% for a weather event; 9-27% for pandemic influenza; 30-56% for a radiological 'dirty' bomb event; and 22-48% for an inhalational anthrax bioterrorism event. Efficacy was consistently identified as an important independent predictor of WTR. CONCLUSIONS: Response willingness deficits in the local public health workforce pose a threat to all-hazards response capacity and health security. Local public health agencies and their stakeholders may incorporate key findings, including identified scenario-based willingness gaps and the importance of efficacy, as targets of preparedness curriculum development efforts and policies for enhancing response willingness. Reasons for an increased willingness in rural cohorts compared to urban cohorts should be further investigated in order to understand and develop methods for improving their overall response.


Assuntos
Atitude do Pessoal de Saúde , Socorristas/psicologia , Governo Local , Prática de Saúde Pública/estatística & dados numéricos , Serviços de Saúde Rural , Serviços Urbanos de Saúde , Adulto , Antraz/prevenção & controle , Antraz/psicologia , Bioterrorismo/prevenção & controle , Bioterrorismo/psicologia , Análise por Conglomerados , Estudos Transversais , Surtos de Doenças/prevenção & controle , Socorristas/estatística & dados numéricos , Características da Família , Feminino , Humanos , Influenza Humana/prevenção & controle , Influenza Humana/psicologia , Exposição por Inalação/prevenção & controle , Masculino , Pessoa de Meia-Idade , Competência Profissional/estatística & dados numéricos , Modelos de Riscos Proporcionais , Psicometria , Fatores de Risco , Terrorismo/prevenção & controle , Terrorismo/psicologia , Estados Unidos , Recursos Humanos
6.
Int J Emerg Ment Health ; 14(2): 95-103, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-23350225

RESUMO

There appears to be virtual universal endorsement of the need for and value of acute "psychological first aid" (PFA) in the wake of trauma and disasters. In this paper, we describe the development of the curriculum for The Johns Hopkins RAPID-PFA model of psychological first aid. We employed an adaptation of the basic framework for the development of a clinical science as recommended by Millon which entailed: historical review, theoretical development, and content validation. The process of content validation of the RAPID-PFA curriculum entailed the assessment of attitudes (confidence in the application of PFA interventions, preparedness in the application of PFA); knowledge related to the application of immediate mental health interventions; and behavior (the ability to recognize clinical markers in the field as assessed via a videotape recognition exercise). Results of the content validation phase suggest the six-hour RAPID-PFA curriculum, initially based upon structural modeling analysis, can improve confidence in the application of PFA interventions, preparedness in the application of PFA, knowledge related to the application of immediate mental health interventions, and the ability to recognize clinical markers in the field as assessed via a videotape recognition exercise.


Assuntos
Intervenção em Crise/educação , Desastres , Serviços de Emergência Psiquiátrica , Acontecimentos que Mudam a Vida , Terrorismo/psicologia , Terapia Cognitivo-Comportamental/educação , Currículo , Empatia , Humanos , Competência Profissional , Psicologia Clínica/educação , Autoimagem , Apoio Social
7.
Int J Emerg Ment Health ; 14(2): 112-22, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-23350227

RESUMO

We describe an academic/faith partnership approach for enhancing the capacity of communities to resist or rebound from the impact of terrorism and other mass casualty events. Representatives of several academic health centers (AHCs) collaborated with leaders of urban Christian-, Jewish-, and Muslim faith-based organizations (FBOs) to design, deliver, and preliminarily evaluate a train-the-trainer approach to enhancing individual competencies in the provision of psychological first aid and in disaster planning for their respective communities. Evidence of partner commitment to, and full participation in, project implementation responsibilities confirmed the feasibility of the overall AHC/FBO collaborative model, and individual post-training, self-report data on perceived effectiveness of the program indicated that the majority of community trainees evaluated the interventions as having significantly increased their: (a) knowledge of disaster mental health concepts; (b) skills (self-efficacy) as providers of psychological first aid and bereavement support services, and (c) (with somewhat less confidence because of module brevity) capabilities of leading disaster preparedness planning efforts within their communities. Notwithstanding the limitations of such early-phase research in ensuring internal and external validity of the interventions, the findings, particularly when combined with those of earlier and subsequent work, support the rationale for continuing to refine this participatory approach to fostering community disaster mental health resilience, and to promoting the translational impact of the model. An especially important (recent) example of the latter is the formal recognition by local and state health departments of program-trained lay volunteers as a vital resource in the continuum of government assets for public health emergency preparedness planning and response.


Assuntos
Fortalecimento Institucional , Comportamento Cooperativo , Desastres , Docentes , Comunicação Interdisciplinar , Incidentes com Feridos em Massa/psicologia , Religião e Psicologia , Resiliência Psicológica , Terrorismo/psicologia , Adulto , Baltimore , Currículo , Planejamento em Desastres/organização & administração , Feminino , Humanos , Capacitação em Serviço/organização & administração , Liderança , Masculino , Pessoa de Meia-Idade , Projetos Piloto
8.
Int J Emerg Ment Health ; 14(2): 125-33, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-23350228

RESUMO

This study sought to investigate the relationship between psychologically-related attitudes/beliefs toward public health emergency response among local health department (LHD) and hospital workers and their willingness to respond to a pandemic influenza emergency scenario and a radiological 'dirty' bomb scenario, to inform workforce resilience-building interventions. LHD and hospital workers participated in a survey based on an established threat- and efficacy-oriented behavioral model (the extended parallel process model) that focused on collection of the aforementioned attitudes, beliefs, and self-reported response willingness. Odds ratios associating psychologically-related attitudes and beliefs with self-reported response willingness were computed Perceived levels of psychological preparedness and support were shown to impact response willingness, with more pronounced effects in the radiological 'dirty' bomb scenario. Compared to those who did not perceive themselves to be psychologically prepared, those who did perceive themselves as prepared had higher odds of self-reported response willingness. The relationship of these perceptions and self-reported willingness to respond in all contexts, both scenarios, and both cohorts was influenced by perceived self-efficacy andperceived family preparedness.


Assuntos
Atitude do Pessoal de Saúde , Intervenção em Crise/organização & administração , Planejamento em Desastres/organização & administração , Recursos Humanos em Hospital/educação , Recursos Humanos em Hospital/psicologia , Saúde Pública , Resiliência Psicológica , Bombas (Dispositivos Explosivos) , Estudos de Coortes , Cultura , Humanos , Influenza Humana/psicologia , Pandemias , Lesões por Radiação/psicologia , Estados Unidos
9.
Am J Public Health ; 101(9): 1580-6, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-21778471

RESUMO

Recognition of petroleum as a finite global resource has spurred increasing interest in the intersection between petroleum scarcity and public health. Local health departments represent a critical yet highly vulnerable component of the public health infrastructure. These frontline agencies currently face daunting resource constraints and rely heavily on petroleum for vital population-based health services. Against this backdrop, petroleum scarcity may necessitate reconfiguring local public health service approaches. We describe the anticipated impacts of petroleum scarcity on local health departments, recommend the use of the 10 Essential Public Health Services as a framework for examining attendant operational challenges and potential responses to them, and describe approaches that local health departments and their stakeholders could consider as part of timely planning efforts.


Assuntos
Órgãos Governamentais , Petróleo/provisão & distribuição , Saúde Pública , Agentes Comunitários de Saúde/organização & administração , Planejamento em Desastres/organização & administração , Humanos , Prática de Saúde Pública , Telemedicina/organização & administração
10.
Public Health Rep ; 125 Suppl 5: 43-50, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-21137131

RESUMO

Local health departments (LHDs) are at the hub of the public health emergency preparedness system. Since the 2003 issuance of Homeland Security Presidential Directive-5, LHDs have faced challenges to comply with a new set of all-hazards, 24/7 organizational response expectations, as well as the National Incident Management System (NIMS). To help local public health practitioners address these challenges, the Centers for Disease Control and Prevention-funded Johns Hopkins Center for Public Health Preparedness (JH-CPHP) created and implemented a face-to-face, public health-specific NIMS training series for LHDs. This article presents the development, evolution, and delivery of the JH-CPHP NIMS training program. In this context, the article also describes a case example of practice-academic collaboration between the National Association of County and City Health Officials and JH-CPHP to develop public health-oriented NIMS course content.


Assuntos
Defesa Civil/educação , Planejamento em Desastres , Educação Profissional em Saúde Pública/organização & administração , Desenvolvimento de Programas , Comportamento Cooperativo , Humanos , Governo Local , Avaliação de Programas e Projetos de Saúde , Administração em Saúde Pública , Estados Unidos
11.
BMC Public Health ; 10: 436, 2010 Jul 26.
Artigo em Inglês | MEDLINE | ID: mdl-20659340

RESUMO

BACKGROUND: Hospital-based providers' willingness to report to work during an influenza pandemic is a critical yet under-studied phenomenon. Witte's Extended Parallel Process Model (EPPM) has been shown to be useful for understanding adaptive behavior of public health workers to an unknown risk, and thus offers a framework for examining scenario-specific willingness to respond among hospital staff. METHODS: We administered an anonymous online EPPM-based survey about attitudes/beliefs toward emergency response, to all 18,612 employees of the Johns Hopkins Hospital from January to March 2009. Surveys were completed by 3426 employees (18.4%), approximately one third of whom were health professionals. RESULTS: Demographic and professional distribution of respondents was similar to all hospital staff. Overall, more than one-in-four (28%) hospital workers indicated they were not willing to respond to an influenza pandemic scenario if asked but not required to do so. Only an additional 10% were willing if required. One-third (32%) of participants reported they would be unwilling to respond in the event of a more severe pandemic influenza scenario. These response rates were consistent across different departments, and were one-third lower among nurses as compared with physicians. Respondents who were hesitant to agree to work additional hours when required were 17 times less likely to respond during a pandemic if asked. Sixty percent of the workers perceived their peers as likely to report to work in such an emergency, and were ten times more likely than others to do so themselves. Hospital employees with a perception of high efficacy had 5.8 times higher declared rates of willingness to respond to an influenza pandemic. CONCLUSIONS: Significant gaps exist in hospital workers' willingness to respond, and the EPPM is a useful framework to assess these gaps. Several attitudinal indicators can help to identify hospital employees unlikely to respond. The findings point to certain hospital-based communication and training strategies to boost employees' response willingness, including promoting pre-event plans for home-based dependents; ensuring adequate supplies of personal protective equipment, vaccines and antiviral drugs for all hospital employees; and establishing a subjective norm of awareness and preparedness.


Assuntos
Atitude do Pessoal de Saúde , Surtos de Doenças , Influenza Humana/epidemiologia , Lealdade ao Trabalho , Recursos Humanos em Hospital , Adulto , Coleta de Dados , Feminino , Humanos , Israel/epidemiologia , Masculino , Pessoa de Meia-Idade , Exposição Ocupacional
12.
Int J Emerg Ment Health ; 12(1): 21-31, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20828087

RESUMO

Disaster mental health research has found that psychological casualties from a given disaster can be expected to far outnumber physical casualties. Amidst a shortage of mental health professionals and against the backdrop of natural disasters, continued terrorism, and pandemic influenza, there is a striking need to expand and operationalize available human resources to enhance the psychological resiliency of those affected. Through the utilization of psychological first aid (PFA) as an early crisis intervention tool, and by virtue of their occupation and experience, nurses are particularly well-suited to assume a leadership role in expanding the disaster mental health presence beyond the existing cadre of mental health clinicians. Here, we characterize the importance of integrating PFA in the context of other nursing functions, to augment mental health surge capacity in disaster settings.


Assuntos
Intervenção em Crise/métodos , Desastres , Educação Continuada em Enfermagem/métodos , Serviços de Emergência Psiquiátrica , Transtornos de Estresse Traumático/psicologia , Intervenção em Crise/educação , Serviços de Emergência Psiquiátrica/métodos , Primeiros Socorros/psicologia , Humanos , Transtornos de Estresse Traumático/etiologia , Transtornos de Estresse Traumático/enfermagem , Capacidade de Resposta ante Emergências/organização & administração , Recursos Humanos
13.
Public Health Rep ; 135(5): 565-570, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32735159

RESUMO

Community resilience is a community's ability to maintain functioning (ie, delivery of services) during and after a disaster event. The Composite of Post-Event Well-Being (COPEWELL) is a system dynamics model of community resilience that predicts a community's disaster-specific functioning over time. We explored COPEWELL's usefulness as a practice-based tool for understanding community resilience and to engage partners in identifying resilience-strengthening strategies. In 2014, along with academic partners, the New York City Department of Health and Mental Hygiene organized an interdisciplinary work group that used COPEWELL to advance cross-sector engagement, design approaches to understand and strengthen community resilience, and identify local data to explore COPEWELL implementation at neighborhood levels. The authors conducted participant interviews and collected shared experiences to capture information on lessons learned. The COPEWELL model led to an improved understanding of community resilience among agency members and community partners. Integration and enhanced alignment of efforts among preparedness, disaster resilience, and community development emerged. The work group identified strategies to strengthen resilience. Searches of neighborhood-level data sets and mapping helped prioritize communities that are vulnerable to disasters (eg, medically vulnerable, socially isolated, low income). These actions increased understanding of available data, identified data gaps, and generated ideas for future data collection. The COPEWELL model can be used to drive an understanding of resilience, identify key geographic areas at risk during and after a disaster, spur efforts to build on local metrics, and result in innovative interventions that integrate and align efforts among emergency preparedness, community development, and broader public health initiatives.


Assuntos
Desastres/estatística & dados numéricos , Modelos Teóricos , Características de Residência/estatística & dados numéricos , Resiliência Psicológica , Capital Social , Estresse Psicológico , Humanos , Cidade de Nova Iorque
14.
Public Health Rep ; 124(2): 295-303, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19320372

RESUMO

OBJECTIVES: In the face of all-hazards preparedness challenges, local and state health department personnel have to date lacked a discrete set of legally and ethically informed public health principles to guide the distribution of scarce resources in crisis settings. To help address this gap, we convened a Summit of academic and practice experts to develop a set of principles for legally and ethically sound public health resource triage decision-making in emergencies. METHODS: The invitation-only Summit, held in Washington, D.C., on June 29, 2006, assembled 20 experts from a combination of academic institutions and nonacademic leadership, policy, and practice settings. The Summit featured a tabletop exercise designed to highlight resource scarcity challenges in a public health infectious disease emergency. This exercise served as a springboard for Summit participants' subsequent identification of 10 public health emergency resource allocation principles through an iterative process. RESULTS: The final product of the Summit was a set of 10 principles to guide allocation decisions involving scarce resources in public health emergencies. The principles are grouped into three categories: obligations to community; balancing personal autonomy and community well-being/benefit; and good preparedness practice. CONCLUSIONS: The 10 Summit-derived principles represent an attempt to link law, ethics, and real-world public health emergency resource allocation practices, and can serve as a useful starting framework to guide further systematic approaches and future research on addressing public health resource scarcity in an all-hazards context.


Assuntos
Planejamento em Desastres/legislação & jurisprudência , Diretrizes para o Planejamento em Saúde , Administração em Saúde Pública/ética , Prática de Saúde Pública/ética , Alocação de Recursos/ética , Tomada de Decisões Gerenciais , Humanos , Características de Residência , Alocação de Recursos/legislação & jurisprudência , Responsabilidade Social , Triagem/ética , Estados Unidos
15.
Prehosp Disaster Med ; 24(3): 223-30, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19618359

RESUMO

There is a common belief that an influenza pandemic not only is inevitable, but that it is imminent. It is further believed by some, and dramatized by a 2006 made-for-television-movie, that such a pandemic will herald an end to life as we know it. Are such claims hyperboles, or does a pandemic represent the most significant threat to public health in the new millennium? Any potential effects of a disease on a population are mediated not only through the pathophysiological mechanisms of the disease itself, but through the psychological and behavioral reactions that such a disease might engender. It is the purpose of this paper to explore the potential psychological and behavioral reactions that may accompany an influenza pandemic.


Assuntos
Planejamento em Desastres , Surtos de Doenças/prevenção & controle , Planejamento em Saúde , Virus da Influenza A Subtipo H5N1 , Influenza Aviária/prevenção & controle , Influenza Humana/prevenção & controle , Transtornos Mentais/prevenção & controle , Saúde Mental , Adaptação Psicológica , Animais , Aves , Saúde Global , Humanos , Influenza Aviária/epidemiologia , Influenza Aviária/transmissão , Influenza Humana/epidemiologia , Influenza Humana/transmissão , Transtornos Mentais/epidemiologia , Estresse Psicológico
16.
Environ Health Perspect ; 116(6): 784-90, 2008 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-18560535

RESUMO

OBJECTIVE: The objective of this study was to evaluate the relations between bone mineral density (BMD) and lead in blood, tibia, and patella and to investigate how BMD modifies these lead biomarkers in older women. DESIGN: In this study, we used cross-sectional analysis. PARTICIPANTS: We studied 112 women, 50-70 years of age, including both whites and African Americans, residing in Baltimore, Maryland. MEASUREMENTS: We measured lumbar spine BMD, blood and bone lead by dual energy X-ray absorptiometry, anodic stripping voltammetry, and (109)Cd-induced K-shell X-ray fluorescence, respectively. We measured vitamin D receptor and apolipoprotein E (APOE) genotypes using standard methods. RESULTS: Mean (+/- SD) BMD and lead levels in blood, tibia, and patella were 1.02+/-0.16 g/cm(2), 3.3+/-2.2 microg/dL, 19.7+/-13.2 microg/g, and 5.7+/-15.3 microg/g, respectively. In adjusted analysis, higher BMD was associated with higher tibia lead levels (p=0.03). BMD was not associated with lead levels in blood or patella. There was evidence of significant effect modification by BMD on relations of physical activity with blood lead levels and by APOE genotype on relations of BMD with tibia lead levels. There was no evidence that BMD modified relations between tibia lead or patella lead and blood lead levels. CONCLUSIONS: We believe that BMD represents the capacity of bone that can store lead, by substitution for calcium, and thus the findings may have relevance for effect-size estimates in persons with higher BMD. RELEVANCE TO CLINICAL PRACTICE: The results have implications for changes in lead kinetics with aging, and thus the related risk of health effects associated with substantial early- and midlife lead exposure in older persons.


Assuntos
Densidade Óssea , Chumbo/análise , Patela/química , Tíbia/química , Saúde da População Urbana/estatística & dados numéricos , Absorciometria de Fóton , Idoso , Apolipoproteínas E/genética , Feminino , Frequência do Gene , Genótipo , Humanos , Chumbo/sangue , Pessoa de Meia-Idade , Receptores de Calcitriol/genética
17.
Nucl Med Biol ; 35(1): 131-41, 2008 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18158952

RESUMO

INTRODUCTION: Noncatabolized thymidine analogs are being developed for use in imaging DNA synthesis. We sought to relate a labeling index measured by immunohistochemical staining bromodeoxyuridine (BUdR) technique to the uptake of (11)C 2'-fluoro-5-methyl-1-beta-d-arabinofuranosyluracil (FMAU) measured with positron emission tomography (PET) in a brain tumor model. METHODS: Adult beagles (n=8) with implanted brain tumors received [(11)C]FMAU and dynamic imaging with arterial sampling. Six dogs were then infused with BUdR (200 mg/m(2)) and sacrificed. Tumor time-activity curves (TACs) obtained from computed-tomography-defined regions of interest were corrected for partial volume effects and crosstalk from brain tissue. Tissue was analyzed for the percentage of tumor volume occupied by viable cells and by viable cells in S-phase as identified by BUdR staining. PET/[(11)C]FMAU and BUdR were compared by linear regression analysis and analysis of variance, as well as by a nonparametric rank correlation test. RESULTS: Tumor standardized uptake values (SUVs) and tumor-to-contralateral-brain uptake ratios at 50 min were 1.6+/-0.4 and 5.5+/-1.2 (n=8; mean+/-S.E.M.), respectively. No (11)C-labeled metabolites were observed in the blood through 60 min. Tumor TACs were well described with a three-compartment/four-parameter model (k(4)=0) and by Patlak analysis. Parametric statistical analysis showed that FMAU clearance from plasma into tumor Compartment 3 (K(FMAU)) was significantly correlated with S-phase percent volume (P=.03), while tumor SUV was significantly correlated with both S-phase percent volume and cell percent volume (P=.02 and .03, respectively). Patlak slope, K(FMAU) and tumor SUV were equivalent with regard to rank correlation analysis, which showed that tumor uptake and trapping of FMAU were correlated with the volume density of dividing cells (P=.0003) rather than nondividing cells (P=.3). CONCLUSIONS: Trapping of [(11)C]FMAU correlated with tumor growth rate, as measured by direct tissue analysis with BUdR in a canine brain tumor model, suggesting that [(11)C]FMAU is useful for the imaging of cell proliferation in cancers.


Assuntos
Arabinofuranosiluracila/análogos & derivados , Neoplasias Encefálicas/patologia , Radioisótopos de Carbono , Tomografia por Emissão de Pósitrons , Animais , Arabinofuranosiluracila/metabolismo , Neoplasias Encefálicas/diagnóstico por imagem , Proliferação de Células , Cães , Fosforilação , Distribuição Tecidual
18.
Acad Med ; 83(3): 298-304, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18316882

RESUMO

As the importance of physician involvement and leadership in crisis preparedness is recognized, the literature suggests that few physicians are adequately trained to practice effectively in a large-scale crisis situation. A logical method for addressing the emergency preparedness training deficiency identified across several medical specialties is to include disaster and emergency preparedness training in residency curricula. In this article, the authors outline the development and implementation of an emergency preparedness curriculum for the Johns Hopkins General Preventive Medicine Residency (JHGPMR) from 2004 to 2006. The curriculum consists of two components. The first was developed for the academic year in the JHGPMR and includes didactic lectures, practical exercises to apply new knowledge, and an opportunity to integrate the knowledge and skills in a real-world exercise. The second, developed for the practicum year of the residency, includes Web-based lectures and online content and culminates in a tabletop preparedness exercise. Topics for both components include weapons of mass destruction, risk communication and personal preparedness, aspects of local emergency response planning, and mental health and psychological aspects of terrorism. On the basis of the emergency preparedness training gap that has been identified in the literature, and the success of the three-year experience in implementing a preparedness training curriculum in the JHGPMR, the authors recommend incorporation of competency-based emergency preparedness training for residencies of all specialties, and offer insights into how the described curriculum could be adapted for use in other residency settings.


Assuntos
Defesa Civil/educação , Currículo , Planejamento em Desastres , Educação de Pós-Graduação em Medicina , Internato e Residência , Liderança , Papel do Médico , Comunicação , Humanos , Maryland , Medicina Preventiva , Desenvolvimento de Programas , Avaliação de Programas e Projetos de Saúde , Medição de Risco
19.
Biosecur Bioterror ; 6(3): 219-26, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18795831

RESUMO

OBJECTIVES: We conducted a survey of corporate preparedness for pandemic influenza among biotechnology and pharmaceutical companies in Montgomery County, Maryland, to determine the level of preparedness for this industry and geographic region. METHODS: The survey, based on the HHS Business Pandemic Influenza Planning Checklist, established whether a company had a preparedness plan specific to pandemic influenza, the contents of its plan, or its reasons for a lack of a plan. RESULTS: A total of 50 companies participated in the survey. Of these, 40 did not have any type of preparedness plan, 3 were drafting plans, 6 had general preparedness plans that could be applied to an influenza pandemic, and only 1 company had a preparedness plan specifically designed to address pandemic influenza. CONCLUSIONS: Biotechnology and pharmaceutical companies in this geographic region are currently not well prepared for pandemic influenza. Public health officials should offer more help, possibly in the form of a model small business preparedness plan, and collaboration between companies should be encouraged to foster sharing of preparedness plans.


Assuntos
Biotecnologia , Defesa Civil , Surtos de Doenças/prevenção & controle , Indústria Farmacêutica , Influenza Humana/prevenção & controle , Política Organizacional , Coleta de Dados , Planejamento em Desastres , Humanos , Influenza Humana/epidemiologia , Maryland
20.
Int J Emerg Ment Health ; 10(3): 169-75, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-19112928

RESUMO

This paper reviews four empirical investigations into the effectiveness of workplace-based crisis intervention programs designed to enhance psychological resiliency. As an extension of a previously published review of effect sizes of workplace-based crisis interventions (Everly et al., 2006), this paper extends the expression of intervention effectiveness by proposing, then utilizing, the odds ratio statistic. It is proposed that the odds ratio is a more useful tool by which to express the practical utility of workplace-based psychosocial interventions. Thus, the use of odds ratios may be a tool that serves to ease the translation of research into practice. That is, odds ratios may aid in expressing the potential usefulness of workplace-based crisis intervention programs in terms that can be easily understood by program managers and policy makers without extensive training in inferential statistics, thereby potentiating increased utilization of such programs as indicated.


Assuntos
Local de Trabalho/psicologia , Local de Trabalho/estatística & dados numéricos , Intervenção em Crise , Humanos , Relações Interpessoais
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