Detalhe da pesquisa
1.
Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.
Cell
; 185(14): 2559-2575.e28, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35688146
2.
R269C variant of ESR1: high prevalence and differential function in a subset of pancreatic cancers.
BMC Cancer
; 20(1): 531, 2020 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32513126
3.
A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal.
PLoS Comput Biol
; 14(2): e1005965, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29415044
4.
Hybrid Capture-Based Comprehensive Genomic Profiling Identifies Lung Cancer Patients with Well-Characterized Sensitizing Epidermal Growth Factor Receptor Point Mutations That Were Not Detected by Standard of Care Testing.
Oncologist
; 23(7): 776-781, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29540602
5.
Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting.
Blood
; 127(24): 3004-14, 2016 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26966091
6.
Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias.
Blood
; 126(22): 2479-83, 2015 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26443624
7.
Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms.
Proc Natl Acad Sci U S A
; 111(50): E5401-10, 2014 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25516983
8.
The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.
Int J Cancer
; 138(4): 881-90, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26314551
9.
Nonamplification ERBB2 genomic alterations in 5605 cases of recurrent and metastatic breast cancer: An emerging opportunity for anti-HER2 targeted therapies.
Cancer
; 122(17): 2654-62, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27284958
10.
Comprehensive genomic profiling of 295 cases of clinically advanced urothelial carcinoma of the urinary bladder reveals a high frequency of clinically relevant genomic alterations.
Cancer
; 122(5): 702-11, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26651075
11.
Evaluation of 122 advanced-stage cutaneous squamous cell carcinomas by comprehensive genomic profiling opens the door for new routes to targeted therapies.
Cancer
; 122(2): 249-57, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26479420
12.
Comprehensive Genomic Profiling of Advanced Penile Carcinoma Suggests a High Frequency of Clinically Relevant Genomic Alterations.
Oncologist
; 21(1): 33-9, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26670666
13.
Comprehensive Genomic Profiling Identifies a Subset of Crizotinib-Responsive ALK-Rearranged Non-Small Cell Lung Cancer Not Detected by Fluorescence In Situ Hybridization.
Oncologist
; 21(6): 762-70, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27245569
14.
Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma.
Oncology
; 90(6): 339-46, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27207748
15.
New class of gene-termini-associated human RNAs suggests a novel RNA copying mechanism.
Nature
; 466(7306): 642-6, 2010 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20671709
16.
Oncogenic alterations in ERBB2/HER2 represent potential therapeutic targets across tumors from diverse anatomic sites of origin.
Oncologist
; 20(1): 7-12, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25480824
17.
Fluorescence in situ hybridization, immunohistochemistry, and next-generation sequencing for detection of EML4-ALK rearrangement in lung cancer.
Oncologist
; 20(3): 316-22, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25721120
18.
Comprehensive Genomic Profiling of Advanced Esophageal Squamous Cell Carcinomas and Esophageal Adenocarcinomas Reveals Similarities and Differences.
Oncologist
; 20(10): 1132-9, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26336083
19.
Prospective comprehensive genomic profiling of advanced gastric carcinoma cases reveals frequent clinically relevant genomic alterations and new routes for targeted therapies.
Oncologist
; 20(5): 499-507, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25882375
20.
Single-step capture and sequencing of natural DNA for detection of BRCA1 mutations.
Genome Res
; 22(2): 340-5, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21765009