Detalhe da pesquisa
1.
Mapping N- to C-terminal allosteric coupling through disruption of a putative CD74 activation site in D-dopachrome tautomerase.
J Biol Chem
; 299(6): 104729, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37080391
2.
Analysis of coordinated NMR chemical shifts to map allosteric regulatory networks in proteins.
Methods
; 209: 40-47, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36535575
3.
Ligand-induced conformational changes enable intersubunit communications in D-dopachrome tautomerase.
Biophys J
; 122(7): 1268-1276, 2023 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36804669
4.
Substrate-independent activation pathways of the CRISPR-Cas9 HNH nuclease.
Biophys J
; 122(24): 4635-4644, 2023 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37936350
5.
Structural Insights into Binding of Remdesivir Triphosphate within the Replication-Transcription Complex of SARS-CoV-2.
Biochemistry
; 61(18): 1966-1973, 2022 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36044776
6.
Insights into Binding of Single-Stranded Viral RNA Template to the Replication-Transcription Complex of SARS-CoV-2 for the Priming Reaction from Molecular Dynamics Simulations.
Biochemistry
; 61(6): 424-432, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35199520
7.
Structural Basis for Reduced Dynamics of Three Engineered HNH Endonuclease Lys-to-Ala Mutants for the Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-Associated 9 (CRISPR/Cas9) Enzyme.
Biochemistry
; 61(9): 785-794, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35420793
8.
Structural and dynamic insights into the HNH nuclease of divergent Cas9 species.
J Struct Biol
; 214(1): 107814, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34871741
9.
How to correct relative voxel scale factors for calculations of vector-difference Fourier maps in cryo-EM.
J Struct Biol
; 214(4): 107902, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36202310
10.
A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.
J Biol Chem
; 297(3): 101061, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34384784
11.
Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage.
J Chem Phys
; 157(22): 225103, 2022 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36546784
12.
The N-terminus of MIF regulates the dynamic profile of residues involved in CD74 activation.
Biophys J
; 120(18): 3893-3900, 2021 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34437846
13.
Mechanism of Inhibition of the Reproduction of SARS-CoV-2 and Ebola Viruses by Remdesivir.
Biochemistry
; 60(24): 1869-1875, 2021 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34110129
14.
A simple approach for reconstruction of non-uniformly sampled pseudo-3D NMR data for accurate measurement of spin relaxation parameters.
J Biomol NMR
; 75(6-7): 213-219, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-33961178
15.
Eigenvector centrality for characterization of protein allosteric pathways.
Proc Natl Acad Sci U S A
; 115(52): E12201-E12208, 2018 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30530700
16.
Mapping the Structural and Dynamic Determinants of pH-Sensitive Heparin Binding to Granulocyte Macrophage Colony Stimulating Factor.
Biochemistry
; 59(38): 3541-3553, 2020 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32897051
17.
Allosteric Motions of the CRISPR-Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics.
J Am Chem Soc
; 142(3): 1348-1358, 2020 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31885264
18.
Altering the allosteric pathway in IGPS suppresses millisecond motions and catalytic activity.
Proc Natl Acad Sci U S A
; 114(17): E3414-E3423, 2017 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28396388
19.
Solution NMR Spectroscopy for the Study of Enzyme Allostery.
Chem Rev
; 116(11): 6323-69, 2016 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26734986
20.
Redox-dependent stability, protonation, and reactivity of cysteine-bound heme proteins.
Proc Natl Acad Sci U S A
; 111(3): E306-15, 2014 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24398520