Detalhe da pesquisa
1.
Studies on enmetazobactam clarify mechanisms of widely used ß-lactamase inhibitors.
Proc Natl Acad Sci U S A
; 119(18): e2117310119, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35486701
2.
Analysis of ß-lactone formation by clinically observed carbapenemases informs on a novel antibiotic resistance mechanism.
J Biol Chem
; 295(49): 16604-16613, 2020 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32963107
3.
Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from Dictyostelium discoideum and Toxoplasma gondii.
J Biol Chem
; 295(49): 16545-16561, 2020 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32934009
4.
Expansion of base excision repair compensates for a lack of DNA repair by oxidative dealkylation in budding yeast.
J Biol Chem
; 294(37): 13629-13637, 2019 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31320474
5.
A Fluorescence-Based Assay for Screening ß-Lactams Targeting the Mycobacterium tuberculosis Transpeptidase LdtMt2.
Chembiochem
; 21(3): 368-372, 2020 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31322798
6.
Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.
Proc Natl Acad Sci U S A
; 114(18): 4667-4672, 2017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28420789
7.
19 Fâ NMR Monitoring of Reversible Protein Post-Translational Modifications: Classâ D ß-Lactamase Carbamylation and Inhibition.
Chemistry
; 25(51): 11837-11841, 2019 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31310409
8.
Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding.
Chemistry
; 25(8): 2019-2024, 2019 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30427558
9.
Inhibition of a viral prolyl hydroxylase.
Bioorg Med Chem
; 27(12): 2405-2412, 2019 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30737136
10.
Non-Hydrolytic ß-Lactam Antibiotic Fragmentation by l,d-Transpeptidases and Serine ß-Lactamase Cysteine Variants.
Angew Chem Int Ed Engl
; 58(7): 1990-1994, 2019 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30569575
11.
Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in ß-lactam biosynthesis.
Nat Prod Rep
; 35(8): 735-756, 2018 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29808887
12.
Structural/mechanistic insights into the efficacy of nonclassical ß-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates.
Mol Microbiol
; 106(3): 492-504, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28876489
13.
A New Mechanism for ß-Lactamases: Class D Enzymes Degrade 1ß-Methyl Carbapenems through Lactone Formation.
Angew Chem Int Ed Engl
; 57(5): 1282-1285, 2018 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29236332
14.
Cyclic Boronates Inhibit All Classes of ß-Lactamases.
Antimicrob Agents Chemother
; 61(4)2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28115348
15.
13C-Carbamylation as a mechanistic probe for the inhibition of class D ß-lactamases by avibactam and halide ions.
Org Biomol Chem
; 15(28): 6024-6032, 2017 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28678295
16.
IFPTarget: A Customized Virtual Target Identification Method Based on Protein-Ligand Interaction Fingerprinting Analyses.
J Chem Inf Model
; 57(7): 1640-1651, 2017 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28661143
17.
Nuclear Magnetic Resonance Solution Structures of Lacticin Q and Aureocin A53 Reveal a Structural Motif Conserved among Leaderless Bacteriocins with Broad-Spectrum Activity.
Biochemistry
; 55(4): 733-42, 2016 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26771761
18.
Solution Structures of Phenol-Soluble Modulins α1, α3, and ß2, Virulence Factors from Staphylococcus aureus.
Biochemistry
; 55(34): 4798-806, 2016 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27525453
19.
Genetic determinants of reutericyclin biosynthesis in Lactobacillus reuteri.
Appl Environ Microbiol
; 81(6): 2032-41, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25576609
20.
Solution structure of acidocin B, a circular bacteriocin produced by Lactobacillus acidophilus M46.
Appl Environ Microbiol
; 81(8): 2910-8, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25681186