Detalhe da pesquisa
1.
The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo.
Nano Lett
; 23(3): 993-1002, 2023 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36701517
2.
The Extent to Which Lipid Nanoparticles Require Apolipoprotein E and Low-Density Lipoprotein Receptor for Delivery Changes with Ionizable Lipid Structure.
Nano Lett
; 22(24): 10025-10033, 2022 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36521071
3.
High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing.
Proc Natl Acad Sci U S A
; 115(42): E9944-E9952, 2018 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30275336
4.
Nucleobase modification by an RNA enzyme.
Nucleic Acids Res
; 45(3): 1345-1354, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28180302
5.
Modifying a Commonly Expressed Endocytic Receptor Retargets Nanoparticles in Vivo.
Nano Lett
; 18(12): 7590-7600, 2018 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30216729
6.
Nanoparticles That Deliver RNA to Bone Marrow Identified by in Vivo Directed Evolution.
J Am Chem Soc
; 140(49): 17095-17105, 2018 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30394729
7.
Substituting racemic ionizable lipids with stereopure ionizable lipids can increase mRNA delivery.
J Control Release
; 353: 270-277, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36423872
8.
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery.
Nat Chem
; 15(4): 508-515, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36864143
9.
High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo.
J Control Release
; 357: 394-403, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37028451
10.
Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery.
Nat Nanotechnol
; 17(8): 871-879, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35768613
11.
Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles.
Nat Nanotechnol
; 17(3): 310-318, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35132167
12.
Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo.
Nat Commun
; 13(1): 4766, 2022 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35970837
13.
Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver.
Nat Biomed Eng
; 6(2): 157-167, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35190679
14.
Therapeutic RNA Delivery for COVID and Other Diseases.
Adv Healthc Mater
; 10(15): e2002022, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33661555
15.
Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs.
Nat Biomed Eng
; 5(9): 1059-1068, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34616046
16.
Nanoparticles containing constrained phospholipids deliver mRNA to liver immune cells in vivo without targeting ligands.
Bioeng Transl Med
; 5(3): e10161, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-33758781
17.
Mild Innate Immune Activation Overrides Efficient Nanoparticle-Mediated RNA Delivery.
Adv Mater
; 32(1): e1904905, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31743531
18.
Cell Subtypes Within the Liver Microenvironment Differentially Interact with Lipid Nanoparticles.
Cell Mol Bioeng
; 12(5): 389-397, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31719922
19.
Constrained Nanoparticles Deliver siRNA and sgRNA to T Cells In Vivo without Targeting Ligands.
Adv Mater
; 31(41): e1902251, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31465135
20.
Nanoparticles Containing Oxidized Cholesterol Deliver mRNA to the Liver Microenvironment at Clinically Relevant Doses.
Adv Mater
; 31(14): e1807748, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30748040