Detalhe da pesquisa
1.
Hepatic Sel1L-Hrd1 ER-associated degradation (ERAD) manages FGF21 levels and systemic metabolism via CREBH.
EMBO J
; 37(22)2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30389665
2.
ERAD deficiency promotes mitochondrial dysfunction and transcriptional rewiring in human hepatic cells.
J Biol Chem
; 295(49): 16743-16753, 2020 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32978261
3.
Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3.
Development
; 141(15): 2939-49, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25053427
4.
Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival.
Proc Natl Acad Sci U S A
; 111(5): E582-91, 2014 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24453213
5.
SEL1L preserves CD8+ T-cell survival and homeostasis by fine-tuning PERK signaling and the IL-15 receptor-mediated mTORC1 axis.
Cell Mol Immunol
; 20(10): 1232-1250, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37644166
6.
Haploid insufficiency of suppressor enhancer Lin12 1-like (SEL1L) protein predisposes mice to high fat diet-induced hyperglycemia.
J Biol Chem
; 286(25): 22275-82, 2011 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21536682
7.
mSEL-1L (Suppressor/enhancer Lin12-like) protein levels influence murine neural stem cell self-renewal and lineage commitment.
J Biol Chem
; 286(21): 18708-19, 2011 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-21454627
8.
Mechano growth factor (MGF) promotes proliferation and inhibits differentiation of porcine satellite cells (PSCs) by down-regulation of key myogenic transcriptional factors.
Mol Cell Biochem
; 370(1-2): 221-30, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22875667
9.
T-cell-specific Sel1L deletion exacerbates EAE by promoting Th1/Th17-cell differentiation.
Mol Immunol
; 149: 13-26, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35696849
10.
Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality.
J Biol Chem
; 285(18): 13694-703, 2010 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20197277
11.
Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells.
Gastroenterology
; 139(1): 270-80, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20398665
12.
Reducing embryonic mtDNA copy number alters epigenetic profile of key hepatic lipolytic genes and causes abnormal lipid accumulation in adult mice.
FEBS J
; 288(23): 6828-6843, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34258867
13.
SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells.
BMC Dev Biol
; 10: 19, 2010 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20170518
14.
Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells.
Dev Biol
; 316(1): 74-86, 2008 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18294628
15.
Endoplasmic Reticulum-Associated Degradation (ERAD) Has a Critical Role in Supporting Glucose-Stimulated Insulin Secretion in Pancreatic ß-Cells.
Diabetes
; 68(4): 733-746, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30626610
16.
Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity.
J Clin Invest
; 128(3): 1125-1140, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29457782
17.
Isolation and expression of zebrafish zinc-finger transcription factor gene tsh1.
Gene Expr Patterns
; 7(3): 318-22, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17035100
18.
ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis.
J Clin Invest
; 127(10): 3897-3912, 2017 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28920920
19.
The ERV-9 LTR enhancer is not blocked by the HS5 insulator and synthesizes through the HS5 site non-coding, long RNAs that regulate LTR enhancer function.
Nucleic Acids Res
; 31(15): 4582-96, 2003 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12888519
20.
XBP1 Regulates the Biosynthetic Capacity of the Mammary Gland During Lactation by Controlling Epithelial Expansion and Endoplasmic Reticulum Formation.
Endocrinology
; 157(1): 417-28, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26562262