Detalhe da pesquisa
1.
Publisher Correction: SERPINB1-mediated checkpoint of inflammatory caspase activation.
Nat Immunol
; 20(5): 664, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30846880
2.
SERPINB1-mediated checkpoint of inflammatory caspase activation.
Nat Immunol
; 20(3): 276-287, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30692621
3.
Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.
Cell
; 156(6): 1193-1206, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24630722
4.
Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.
Mol Cell
; 64(2): 236-250, 2016 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27746017
5.
Molecular mechanism for NLRP6 inflammasome assembly and activation.
Proc Natl Acad Sci U S A
; 116(6): 2052-2057, 2019 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30674671
6.
Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule.
Chembiochem
; 22(12): 2107-2110, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33838082
7.
Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.
Proc Natl Acad Sci U S A
; 115(43): 10845-10852, 2018 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30279182
8.
Instant Hydrogelation Inspired by Inflammasomes.
Angew Chem Int Ed Engl
; 56(26): 7579-7583, 2017 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28481474
9.
The Inflammasome Adaptor ASC Induces Procaspase-8 Death Effector Domain Filaments.
J Biol Chem
; 290(49): 29217-30, 2015 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26468282
10.
A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants.
Cell Chem Biol
; 28(8): 1158-1168.e13, 2021 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33705687
11.
PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity.
Cancer Cell
; 39(9): 1214-1226.e10, 2021 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34375612
12.
In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement.
Cell Chem Biol
; 27(7): 877-887.e14, 2020 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32679093
13.
Enabling drug discovery for the PARP protein family through the detection of mono-ADP-ribosylation.
Biochem Pharmacol
; 167: 97-106, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31075269
14.
A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly.
J Exp Med
; 213(5): 771-90, 2016 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27069117
15.
Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism.
Nat Struct Mol Biol
; 23(5): 416-25, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27043298
16.
Structural mechanisms of inflammasome assembly.
FEBS J
; 282(3): 435-44, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25354325
17.
Plasticity in PYD assembly revealed by cryo-EM structure of the PYD filament of AIM2.
Cell Discov
; 12015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26583071
18.
Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.
Science
; 350(6259): 404-9, 2015 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26449474
19.
Crystal structure of the F27G AIM2 PYD mutant and similarities of its self-association to DED/DED interactions.
J Mol Biol
; 426(7): 1420-7, 2014 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24406744
20.
Heat shock protein 70 inhibitors. 2. 2,5'-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70.
J Med Chem
; 57(4): 1208-24, 2014 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24548239