Detalhe da pesquisa
1.
HMGB1-RAGE axis contributes to myocardial ischemia/reperfusion injury via regulation of cardiomyocyte autophagy and apoptosis in diabetic mice.
Biol Chem
; 405(3): 167-176, 2024 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37768929
2.
Y4 RNA fragments from cardiosphere-derived cells ameliorate diabetic myocardial ischemiaâreperfusion injury by inhibiting protein kinase C ß-mediated macrophage polarization.
Cardiovasc Diabetol
; 23(1): 202, 2024 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38867293
3.
Adaptive Control for Virtual Synchronous Generator Parameters Based on Soft Actor Critic.
Sensors (Basel)
; 24(7)2024 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38610247
4.
Inhibition of miR-143-3p alleviates myocardial ischemia reperfusion injury via limiting mitochondria-mediated apoptosis.
Biol Chem
; 404(6): 619-631, 2023 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36780323
5.
Robust, fast and sensitive near-infrared continuous-filtering Vernier spectrometer.
Opt Express
; 29(19): 30155-30167, 2021 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34614744
6.
Assessment and Confirmation of Species Difference in Nonlinear Pharmacokinetics of Atipamezole with Physiologically Based Pharmacokinetic Modeling.
Drug Metab Dispos
; 48(1): 41-51, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31699808
7.
Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors.
Drug Metab Dispos
; 48(3): 217-229, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31911485
8.
Qualification of impurities based on metabolite data.
Regul Toxicol Pharmacol
; 110: 104524, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31734179
9.
In vitro and in vivo methods to assess pharmacokinetic drug- drug interactions in drug discovery and development.
Biopharm Drug Dispos
; 41(1-2): 3-31, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31778578
10.
Time-resolved continuous-filtering Vernier spectroscopy of H2O and OH radical in a flame.
Opt Express
; 27(21): 29521-29533, 2019 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31684212
11.
Development and validation of an LC-MS/MS method for the determination of a novel thienoquinolin urea transporter inhibitor PU-48 in rat plasma and its application to a pharmacokinetic study.
Biomed Chromatogr
; 32(4)2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29193233
12.
Effects of crystalline state and self-nanoemulsifying drug delivery system (SNEDDS) on oral bioavailability of the novel anti-HIV compound 6-benzyl-1-benzyloxymethyl-5-iodouracil in rats.
Drug Dev Ind Pharm
; 44(2): 329-337, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29113503
13.
Effects of functional CYP2C8,CYP2C9,CYP3A5,and ABCB1 genetic variants on the pharmacokinetics of insulin sensitizer pioglitazone in Chinese Han individuals.
Pharmacogenet Genomics
; 27(4): 125-134, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28099407
14.
Identification of cytochrome P450s involved in the metabolism of 6-benzyl-1-benzyloxymethyl-5-iodouracil (W-1) using human recombinant enzymes and rat liver microsomes in vitro.
Xenobiotica
; 47(8): 667-672, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27910729
15.
Evaluation of a New Molecular Entity as a Victim of Metabolic Drug-Drug Interactions-an Industry Perspective.
Drug Metab Dispos
; 44(8): 1399-423, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27052879
16.
Development and validation of a high performance liquid chromatography method for determination of 6-benzyl-1-benzyloxymethyl-5-iodouracil (W-1), a novel non-nucleoside reverse transcriptase inhibitor and its application to a pharmacokinetic study in rats.
Biomed Chromatogr
; 29(10): 1548-52, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25808138
17.
Assessment of cytochrome P450-mediated drug-drug interaction potential of orteronel and exposure changes in patients with renal impairment using physiologically based pharmacokinetic modeling and simulation.
Biopharm Drug Dispos
; 35(9): 543-52, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25264242
18.
Characterization of preclinical in vitro and in vivo ADME properties and prediction of human PK using a physiologically based pharmacokinetic model for YQA-14, a new dopamine D3 receptor antagonist candidate for treatment of drug addiction.
Biopharm Drug Dispos
; 35(5): 296-307, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24647883
19.
Endothelial progenitor cell-derived extracellular vesicles: the world of potential prospects for the treatment of cardiovascular diseases.
Cell Biosci
; 14(1): 72, 2024 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38840175
20.
The lemon genome and DNA methylome unveil epigenetic regulation of citric acid biosynthesis during fruit development.
Hortic Res
; 11(3): uhae005, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38464476