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Malar J ; 13: 226, 2014 Jun 07.
Artigo em Inglês | MEDLINE | ID: mdl-24906879

RESUMO

According to current estimates, Plasmodium malariae is not very common in Senegal, as more than 98% of malaria cases are suspected to be due to Plasmodium falciparum. However, it is possible that other malarial species are being under-reported or misdiagnosed. This is a report of a case of P. malariae in a 30-year-old man previously hospitalized with acute kidney injury after treatment with quinine and re-hospitalized three months later. He was diagnosed with renal cortical necrosis post malaria treatment. Plasmodium malariae was identified with light microscope and confirmed using species-specific small-subunit rRNA (ssrRNA) amplification.The patient was treated for malaria with intravenous quinine for seven days, followed by three days of oral treatment; the bacterial infection was treated using ceftriaxone during the first hospitalization and ciprofloxacin associated with ceftriaxone the second time. He also had four rounds of dialysis after which he partially recovered the renal function. Given the complications that can be caused by P. malariae infection, it should be systematically looked for, even if the predominant species is P. falciparum in Senegal.


Assuntos
Injúria Renal Aguda/diagnóstico , Injúria Renal Aguda/patologia , Malária/complicações , Malária/parasitologia , Plasmodium malariae/isolamento & purificação , Adulto , Antibacterianos/uso terapêutico , Antimaláricos/uso terapêutico , Infecções Bacterianas/diagnóstico , Infecções Bacterianas/tratamento farmacológico , Ceftriaxona/uso terapêutico , Humanos , Malária/diagnóstico , Malária/tratamento farmacológico , Masculino , Microscopia , Técnicas de Amplificação de Ácido Nucleico , Quinina/uso terapêutico , RNA Ribossômico 18S/genética , Diálise Renal , Senegal , Resultado do Tratamento
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