Detalhe da pesquisa
1.
Minimal brain PBPK model to support the preclinical and clinical development of antibody therapeutics for CNS diseases.
J Pharmacokinet Pharmacodyn
; 48(6): 861-871, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34378151
2.
The role of patient-based treatment planning in peptide receptor radionuclide therapy.
Eur J Nucl Med Mol Imaging
; 43(5): 871-880, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26577941
3.
Formal anti-carbopalladation reactions of non-activated alkynes: requirements, mechanistic insights, and applications.
Angew Chem Int Ed Engl
; 54(13): 4119-23, 2015 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25651006
4.
Effects of metal coordination on the π-system of the 2,5-bis-{(pyrrolidino)-methyl}-pyrrole pincer ligand.
Inorg Chem
; 52(16): 9539-48, 2013 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23902578
5.
Considering developmental neurotoxicity in vitro data for human health risk assessment using physiologically-based kinetic modeling: deltamethrin case study.
Toxicol Sci
; 192(1): 59-70, 2023 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36637193
6.
A systematic review of kidney-on-a-chip-based models to study human renal (patho-)physiology.
Dis Model Mech
; 16(6)2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37334839
7.
Studying metabolism with multi-organ chips: new tools for disease modelling, pharmacokinetics and pharmacodynamics.
Open Biol
; 12(3): 210333, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35232251
8.
Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system.
Commun Biol
; 4(1): 1080, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34526653
9.
Gut-Liver Physiomimetics Reveal Paradoxical Modulation of IBD-Related Inflammation by Short-Chain Fatty Acids.
Cell Syst
; 10(3): 223-239.e9, 2020 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32191873
10.
Translational Assessment of Drug-Induced Proximal Tubule Injury Using a Kidney Microphysiological System.
CPT Pharmacometrics Syst Pharmacol
; 8(5): 316-325, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30869201
11.
Efficient synthesis of helical tetrasubstituted alkenes as potential molecular switches: a two-component palladium-catalyzed triple domino process.
Angew Chem Int Ed Engl
; 52(13): 3668-71, 2013 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23418082
12.
Total synthesis of linoxepin through a palladium-catalyzed domino reaction.
Angew Chem Int Ed Engl
; 52(11): 3191-4, 2013 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23404683
13.
Benchmarking lithium amide versus amine bonding by charge density and energy decomposition analysis arguments.
Chem Sci
; 9(12): 3111-3121, 2018 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29732094
14.
Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies.
Sci Rep
; 8(1): 8015, 2018 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29789564
15.
Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies.
Sci Rep
; 8(1): 4530, 2018 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29540740
16.
Multi-functional scaling methodology for translational pharmacokinetic and pharmacodynamic applications using integrated microphysiological systems (MPS).
Integr Biol (Camb)
; 9(4): 290-302, 2017 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28267162
17.
Optimized Peptide Amount and Activity for 9°Y-Labeled DOTATATE Therapy.
J Nucl Med
; 57(4): 503-8, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26678617
18.
Dependence of treatment planning accuracy in peptide receptor radionuclide therapy on the sampling schedule.
EJNMMI Res
; 6(1): 30, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27015662
19.
Physiologically based pharmacokinetic modeling of (18)F-SiFAlin-Asp3-PEG1-TATE in AR42J tumor bearing mice.
Nucl Med Biol
; 43(4): 243-6, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27067044
20.
Physiologically Based Pharmacokinetic Modeling Is Essential in 90Y-Labeled Anti-CD66 Radioimmunotherapy.
PLoS One
; 10(5): e0127934, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26010360