Pesquisa | BVS Integralidade em Saúde

1.

Julia for biologists.

Roesch, Elisabeth; Greener, Joe G; MacLean, Adam L; Nassar, Huda; Rackauckas, Christopher; Holy, Timothy E; Stumpf, Michael P H.

Nat Methods ; 20(5): 655-664, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37024649

2.

A single-cell resolved cell-cell communication model explains lineage commitment in hematopoiesis.

Rommelfanger, Megan K; MacLean, Adam L.

Development ; 148(24)2021 12 15.

Artigo em Inglês | MEDLINE | ID: mdl-34935903

3.

Age-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in mice.

Suo, Miaomiao; Rommelfanger, Megan K; Chen, Yulin; Amro, Elias Moris; Han, Bing; Chen, Zhiyang; Szafranski, Karol; Chakkarappan, Sundaram Reddy; Boehm, Bernhard O; MacLean, Adam L; Rudolph, K Lenhard.

Blood ; 139(17): 2653-2665, 2022 04 28.

Artigo em Inglês | MEDLINE | ID: mdl-35231105

4.

RVAgene: generative modeling of gene expression time series data.

Mitra, Raktim; MacLean, Adam L.

Bioinformatics ; 37(19): 3252-3262, 2021 Oct 11.

Artigo em Inglês | MEDLINE | ID: mdl-33974008

5.

Author Correction: Julia for biologists.

Roesch, Elisabeth; Greener, Joe G; MacLean, Adam L; Nassar, Huda; Rackauckas, Christopher; Holy, Timothy E; Stumpf, Michael P H.

Nat Methods ; 20(5): 771, 2023 May.

Artigo em Inglês | MEDLINE | ID: mdl-37120675

6.

An Ovol2-Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation.

Haensel, Daniel; Sun, Peng; MacLean, Adam L; Ma, Xianghui; Zhou, Yuan; Stemmler, Marc P; Brabletz, Simone; Berx, Geert; Plikus, Maksim V; Nie, Qing; Brabletz, Thomas; Dai, Xing.

EMBO Rep ; 20(1)2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30413481

7.

Cell lineage and communication network inference via optimization for single-cell transcriptomics.

Wang, Shuxiong; Karikomi, Matthew; MacLean, Adam L; Nie, Qing.

Nucleic Acids Res ; 47(11): e66, 2019 06 20.

Artigo em Inglês | MEDLINE | ID: mdl-30923815

8.

Voices carry.

MacLean, Adam L.

Nat Chem Biol ; 19(5): 540-541, 2023 May.

Artigo em Inglês | MEDLINE | ID: mdl-36635562

9.

Transcriptomics reveals complex kinetics of dorsal-ventral patterning gene expression in the mandibular arch.

Sharma, Praveer P; MacLean, Adam L; Meinecke, Lina; Clouthier, David E; Nie, Qing; Schilling, Thomas F.

Genesis ; 57(1): e23275, 2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30561090

10.

scEpath: energy landscape-based inference of transition probabilities and cellular trajectories from single-cell transcriptomic data.

Jin, Suoqin; MacLean, Adam L; Peng, Tao; Nie, Qing.

Bioinformatics ; 34(12): 2077-2086, 2018 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-29415263

11.

Concise Review: Stem Cell Population Biology: Insights from Hematopoiesis.

MacLean, Adam L; Lo Celso, Cristina; Stumpf, Michael P H.

Stem Cells ; 35(1): 80-88, 2017 01.

Artigo em Inglês | MEDLINE | ID: mdl-27671750

12.

Single Cell Phenotyping Reveals Heterogeneity Among Hematopoietic Stem Cells Following Infection.

MacLean, Adam L; Smith, Maia A; Liepe, Juliane; Sim, Aaron; Khorshed, Reema; Rashidi, Narges M; Scherf, Nico; Krinner, Axel; Roeder, Ingo; Lo Celso, Cristina; Stumpf, Michael P H.

Stem Cells ; 35(11): 2292-2304, 2017 11.

Artigo em Inglês | MEDLINE | ID: mdl-28833970

13.

Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis.

Lambert, Ben; MacLean, Adam L; Fletcher, Alexander G; Combes, Alexander N; Little, Melissa H; Byrne, Helen M.

J Math Biol ; 76(7): 1673-1697, 2018 06.

Artigo em Inglês | MEDLINE | ID: mdl-29392399

14.

Parameter-free methods distinguish Wnt pathway models and guide design of experiments.

MacLean, Adam L; Rosen, Zvi; Byrne, Helen M; Harrington, Heather A.

Proc Natl Acad Sci U S A ; 112(9): 2652-7, 2015 Mar 03.

Artigo em Inglês | MEDLINE | ID: mdl-25730853

15.

The ecology in the hematopoietic stem cell niche determines the clinical outcome in chronic myeloid leukemia.

MacLean, Adam L; Filippi, Sarah; Stumpf, Michael P H.

Proc Natl Acad Sci U S A ; 111(10): 3883-8, 2014 Mar 11.

Artigo em Inglês | MEDLINE | ID: mdl-24567385

16.

The diverse landscape of modeling in single-cell biology.

MacLean, Adam L; Nie, Qing.

Phys Biol ; 18(5)2021 06 30.

Artigo em Inglês | MEDLINE | ID: mdl-34283805

17.

Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia.

Crowell, Helena L; MacLean, Adam L; Stumpf, Michael P H.

J Theor Biol ; 401: 43-53, 2016 07 21.

Artigo em Inglês | MEDLINE | ID: mdl-27130539

18.

Developmental hematopoietic stem cell variation explains clonal hematopoiesis later in life.

Kreger, Jesse; Mooney, Jazlyn A; Shibata, Darryl; MacLean, Adam L.

bioRxiv ; 2024 Mar 05.

Artigo em Inglês | MEDLINE | ID: mdl-38496542

19.

Gastrulation-stage gene expression in Nipbl^+/- mouse embryos foreshadows the development of syndromic birth defects.

Chea, Stephenson; Kreger, Jesse; Lopez-Burks, Martha E; MacLean, Adam L; Lander, Arthur D; Calof, Anne L.

bioRxiv ; 2024 Feb 13.

Artigo em Inglês | MEDLINE | ID: mdl-37905011

20.

Gastrulation-stage gene expression in Nipbl^+/- mouse embryos foreshadows the development of syndromic birth defects.

Chea, Stephenson; Kreger, Jesse; Lopez-Burks, Martha E; MacLean, Adam L; Lander, Arthur D; Calof, Anne L.

Sci Adv ; 10(12): eadl4239, 2024 Mar 22.

Artigo em Inglês | MEDLINE | ID: mdl-38507484

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Julia for biologists.

A single-cell resolved cell-cell communication model explains lineage commitment in hematopoiesis.

Age-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in mice.

RVAgene: generative modeling of gene expression time series data.

Author Correction: Julia for biologists.

An Ovol2-Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation.

Cell lineage and communication network inference via optimization for single-cell transcriptomics.

Voices carry.

Transcriptomics reveals complex kinetics of dorsal-ventral patterning gene expression in the mandibular arch.

scEpath: energy landscape-based inference of transition probabilities and cellular trajectories from single-cell transcriptomic data.

Concise Review: Stem Cell Population Biology: Insights from Hematopoiesis.

Single Cell Phenotyping Reveals Heterogeneity Among Hematopoietic Stem Cells Following Infection.

Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis.

Parameter-free methods distinguish Wnt pathway models and guide design of experiments.

The ecology in the hematopoietic stem cell niche determines the clinical outcome in chronic myeloid leukemia.

The diverse landscape of modeling in single-cell biology.

Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia.

Developmental hematopoietic stem cell variation explains clonal hematopoiesis later in life.

Gastrulation-stage gene expression in Nipbl^+/- mouse embryos foreshadows the development of syndromic birth defects.

Gastrulation-stage gene expression in Nipbl^+/- mouse embryos foreshadows the development of syndromic birth defects.