Detalhe da pesquisa
1.
Supply and demand: Cellular nutrient uptake and exchange in cancer.
Mol Cell
; 81(18): 3731-3748, 2021 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34547236
2.
Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells.
Mol Cell
; 61(2): 210-21, 2016 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26774282
3.
Corrigendum: Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Nature
; 548(7665): 122, 2017 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28770843
4.
Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Nature
; 544(7650): 372-376, 2017 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28425994
5.
Sensitisation of cancer cells to radiotherapy by serine and glycine starvation.
Br J Cancer
; 127(10): 1773-1786, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36115879
6.
Localization of NADPH production: a wheel within a wheel.
Mol Cell
; 55(2): 158-60, 2014 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25038411
7.
Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.
Nature
; 493(7433): 542-6, 2013 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23242140
8.
Serine is a natural ligand and allosteric activator of pyruvate kinase M2.
Nature
; 491(7424): 458-462, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23064226
9.
One-carbon metabolism in cancer.
Br J Cancer
; 116(12): 1499-1504, 2017 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28472819
10.
Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models.
Cell Death Dis
; 15(5): 382, 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38821960
11.
Phenotypic profiling of solute carriers characterizes serine transport in cancer.
Nat Metab
; 5(12): 2148-2168, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38066114
12.
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target.
Nat Metab
; 5(8): 1303-1318, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37580540
13.
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency.
Cell Rep
; 42(5): 112372, 2023 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37086404
14.
Global metabolic alterations in colorectal cancer cells during irinotecan-induced DNA replication stress.
Cancer Metab
; 10(1): 10, 2022 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35787728
15.
Mitochondrial ROS signalling requires uninterrupted electron flow and is lost during ageing in flies.
Geroscience
; 44(4): 1961-1974, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35355221
16.
SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis.
Cell Rep
; 40(7): 111233, 2022 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35977477
17.
Autophagy promotes cell survival by maintaining NAD levels.
Dev Cell
; 57(22): 2584-2598.e11, 2022 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36413951
18.
mTORC1 activity is supported by spatial association with focal adhesions.
J Cell Biol
; 220(5)2021 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33635313
19.
Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy.
Nat Commun
; 12(1): 366, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33446657
20.
Mechanistic insights into p53-regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells.
Mol Oncol
; 15(12): 3404-3429, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34258881