Detalhe da pesquisa
1.
Ibrexafungerp: An orally active ß-1,3-glucan synthesis inhibitor.
Bioorg Med Chem Lett
; 32: 127661, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33160023
2.
MK-5204: An orally active ß-1,3-glucan synthesis inhibitor.
Bioorg Med Chem Lett
; 30(17): 127357, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32738971
3.
Novel orally active inhibitors of ß-1,3-glucan synthesis derived from enfumafungin.
Bioorg Med Chem Lett
; 25(24): 5813-8, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26542966
4.
Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor.
ACS Med Chem Lett
; 14(2): 199-210, 2023 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36793435
5.
Discovery of Nanomolar DCAF1 Small Molecule Ligands.
J Med Chem
; 66(7): 5041-5060, 2023 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36948210
6.
Synthesis and biological evaluation of antifungal derivatives of enfumafungin as orally bioavailable inhibitors of ß-1,3-glucan synthase.
Bioorg Med Chem Lett
; 22(22): 6811-6, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22672801
7.
Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells.
J Mol Biol
; 433(23): 167294, 2021 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34662547
8.
Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma.
J Med Chem
; 63(17): 10061-10085, 2020 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32787083
9.
Strategies for the solid-phase diversification of poly-L-proline-type II peptide mimic scaffolds and peptide scaffolds through guanidinylation.
J Org Chem
; 73(19): 7593-602, 2008 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-18754643
10.
Virus-tumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-triggered caspase-2 cell death.
Cancer Cell
; 20(4): 443-56, 2011 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22014571
11.
Synthesis of conformationally constrained lysine analogues.
J Org Chem
; 71(13): 5004-7, 2006 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-16776535