Detalhe da pesquisa
1.
In silico and crystallographic studies identify key structural features of biliverdin IXß reductase inhibitors having nanomolar potency.
J Biol Chem
; 293(15): 5431-5446, 2018 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29487133
2.
BLVRB redox mutation defines heme degradation in a metabolic pathway of enhanced thrombopoiesis in humans.
Blood
; 128(5): 699-709, 2016 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27207795
3.
Enzymatic Activity and Thermodynamic Stability of Biliverdin IXß Reductase Are Maintained by an Active Site Serine.
Chemistry
; 23(8): 1891-1900, 2017 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27897348
4.
Computational and experimental studies on the catalytic mechanism of biliverdin-IXbeta reductase.
Biochem J
; 411(3): 475-84, 2008 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18241201
5.
Activation of biliverdin-IXalpha reductase by inorganic phosphate and related anions.
Biochem J
; 405(1): 61-7, 2007 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17402939
6.
Suppression of human alloreactive T cells by linear tetrapyrroles; relevance for transplantation.
Transl Res
; 178: 81-94.e2, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27497182
7.
Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for 'ping pong' kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione.
FEBS J
; 278(2): 273-81, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21134126
8.
Chromatofocusing.
Methods Mol Biol
; 244: 233-7, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-14970561
9.
The effect of pH on the initial rate kinetics of the dimeric biliverdin-IXalpha reductase from the cyanobacterium Synechocystis PCC6803.
FEBS J
; 276(16): 4414-25, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19614741
10.
The use of synthetic linear tetrapyrroles to probe the verdin sites of human biliverdin-IXalpha reductase and human biliverdin-IXbeta reductase.
FEBS J
; 276(16): 4405-13, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19614742