Detalhe da pesquisa
1.
Randomized, Controlled Trial of the FGF21 Analogue Pegozafermin in NASH.
N Engl J Med
; 389(11): 998-1008, 2023 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37356033
2.
MASH Resolution Index: development and validation of a non-invasive score to detect histological resolution of MASH.
Gut
; 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38418210
3.
The Novel GlycoPEGylated FGF21 Analog Pegozafermin Activates Human FGF Receptors and Improves Metabolic and Liver Outcomes in Diabetic Monkeys and Healthy Human Volunteers.
J Pharmacol Exp Ther
; 387(2): 204-213, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37562970
4.
Randomized Trial of Pegozafermin in NASH. Reply.
N Engl J Med
; 389(23): 2210, 2023 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38055266
5.
Population Pharmacokinetics and Pharmacodynamics of Pegozafermin in Patients with Nonalcoholic Steatohepatitis.
Clin Pharmacol Ther
; 114(6): 1323-1331, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37696614
6.
Safety, pharmacokinetics, and pharmacodynamics of pegozafermin in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 1b/2a multiple-ascending-dose study.
Lancet Gastroenterol Hepatol
; 8(2): 120-132, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36521501
7.
Clinical trial: Effects of pegozafermin on the liver and on metabolic comorbidities in subjects with biopsy-confirmed nonalcoholic steatohepatitis.
Aliment Pharmacol Ther
; 58(10): 1005-1015, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37718721
8.
Disease severity in sibling pairs with type 1 Gaucher disease.
J Inherit Metab Dis
; 33(1): 79-83, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20049528
9.
Combination immunomodulator and antibiotic treatment in patients with inflammatory bowel disease and clostridium difficile infection.
Clin Gastroenterol Hepatol
; 7(9): 981-7, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19523534
10.
Epstein-barr virus-related diarrhea or exacerbation of inflammatory bowel disease: diagnostic dilemma.
J Clin Microbiol
; 47(5): 1588-90, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19279175
11.
Letter: Severe underweight and sarcopenia in decompensated cirrhosis are associated with high FGF21 levels-authors' reply.
Aliment Pharmacol Ther
; 59(6): 797-798, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38401143
12.
Alleviation of acute and chronic graft-versus-host disease in a murine model is associated with glucocerebroside-enhanced natural killer T lymphocyte plasticity.
Transplantation
; 83(4): 458-67, 2007 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-17318079
13.
Laquinimod Safety Profile: Pooled Analyses from the ALLEGRO and BRAVO Trials.
Int J MS Care
; 19(1): 16-24, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28243182
14.
Alleviation of chronic GVHD in mice by oral immuneregulation toward recipient pretransplant splenocytes does not jeopardize the graft versus leukemia effect.
Hum Immunol
; 66(3): 231-40, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15784461
15.
Oral immune regulation: a novel method for modulation of anti-viral immunity.
J Clin Virol
; 31 Suppl 1: S63-8, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15567096
16.
A rapid quantitative D-dimer assay at admission correlates with the severity of community acquired pneumonia.
Blood Coagul Fibrinolysis
; 14(8): 745-8, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14614354
17.
Prevalence and clinical impact of endoscopic pseudomembranes in patients with inflammatory bowel disease and Clostridium difficile infection.
J Crohns Colitis
; 4(2): 194-8, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21122505
18.
Glucocerebroside ameliorates the metabolic syndrome in OB/OB mice.
J Pharmacol Exp Ther
; 319(1): 105-10, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16815870
19.
Amelioration of non-alcoholic steatohepatitis and glucose intolerance in ob/ob mice by oral immune regulation towards liver-extracted proteins is associated with elevated intrahepatic NKT lymphocytes and serum IL-10 levels.
J Pathol
; 208(1): 74-81, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16261527
20.
A double-blind clinical trial for treatment of Crohn's disease by oral administration of Alequel, a mixture of autologous colon-extracted proteins: a patient-tailored approach.
Am J Gastroenterol
; 101(3): 561-8, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16542292