Detalhe da pesquisa
1.
Oxidized cholesteryl ester induces exocytosis of dysfunctional lysosomes in lipidotic macrophages.
Traffic
; 24(7): 284-307, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37129279
2.
Current methods to analyze lysosome morphology, positioning, motility and function.
Traffic
; 23(5): 238-269, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35343629
3.
Cholesteryl hemiazelate causes lysosome dysfunction impacting vascular smooth muscle cell homeostasis.
J Cell Sci
; 135(5)2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34528688
4.
Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation.
J Lipid Res
; 64(9): 100419, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37482218
5.
The development of a broad-spectrum retaining ß-exo-galactosidase activity-based probe.
Org Biomol Chem
; 21(38): 7813-7820, 2023 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37724332
6.
Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease.
Neurobiol Dis
; 175: 105919, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36347423
7.
Human glucocerebrosidase mediates formation of xylosyl-cholesterol by ß-xylosidase and transxylosidase reactions.
J Lipid Res
; 62: 100018, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33361282
8.
Lysosomal storage disorders - challenges, concepts and avenues for therapy: beyond rare diseases.
J Cell Sci
; 132(2)2019 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30651381
9.
GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice.
Int J Mol Sci
; 22(5)2021 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33802460
10.
A Specific Activity-Based Probe to Monitor Family GH59 Galactosylceramidase, the Enzyme Deficient in Krabbe Disease.
Chembiochem
; 18(4): 402-412, 2017 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28000364
11.
Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular ß-glucosidases.
J Lipid Res
; 57(3): 451-63, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26724485
12.
Lyso-glycosphingolipid abnormalities in different murine models of lysosomal storage disorders.
Mol Genet Metab
; 117(2): 186-93, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26750750
13.
Lentiviral gene therapy using cellular promoters cures type 1 Gaucher disease in mice.
Mol Ther
; 23(5): 835-844, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25655314
14.
The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation.
J Lipid Res
; 54(8): 2174-2184, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23733886
15.
Cholesteryl Hemiazelate Present in Cardiovascular Disease Patients Causes Lysosome Dysfunction in Murine Fibroblasts.
Cells
; 12(24)2023 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38132146
16.
A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution.
Front Bioeng Biotechnol
; 11: 1128371, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36911201
17.
Novel activity-based probes for broad-spectrum profiling of retaining ß-exoglucosidases inâ situ and inâ vivo.
Angew Chem Int Ed Engl
; 51(50): 12529-33, 2012 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23139194
18.
Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models.
Autophagy
; 18(5): 1127-1151, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35287553
19.
Delay of EGF-Stimulated EGFR Degradation in Myotonic Dystrophy Type 1 (DM1).
Cells
; 11(19)2022 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36230978
20.
Lysosome (Dys)function in Atherosclerosis-A Big Weight on the Shoulders of a Small Organelle.
Front Cell Dev Biol
; 9: 658995, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33855029