Detalhe da pesquisa
1.
Protein mishandling and impaired lysosomal proteolysis generated through calcium dysregulation in Alzheimer's disease.
Proc Natl Acad Sci U S A
; 119(49): e2211999119, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36442130
2.
Human-Induced Neurons from Presenilin 1 Mutant Patients Model Aspects of Alzheimer's Disease Pathology.
Int J Mol Sci
; 21(3)2020 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32033164
3.
NPY Induces Stress Resilience via Downregulation of Ih in Principal Neurons of Rat Basolateral Amygdala.
J Neurosci
; 38(19): 4505-4520, 2018 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29650696
4.
Targeting Amyloid-ß Precursor Protein, APP, Splicing with Antisense Oligonucleotides Reduces Toxic Amyloid-ß Production.
Mol Ther
; 26(6): 1539-1551, 2018 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29628304
5.
Modification of pax6 and olig2 expression in adult hippocampal neurogenesis selectively induces stem cell fate and alters both neuronal and glial populations.
Stem Cells
; 30(3): 500-9, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22162276
6.
Engineered neurogenesis in naïve adult rat cortex by Ngn2-mediated neuronal reprogramming of resident oligodendrocyte progenitor cells.
Front Neurosci
; 17: 1237176, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37662111
7.
Neprilysin-2 is an important ß-amyloid degrading enzyme.
Am J Pathol
; 178(1): 306-12, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21224067
8.
Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice.
Nature
; 438(7068): 662-6, 2005 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16244648
9.
Induced Neurons for Disease Modeling and Repair: A Focus on Non-fibroblastic Cell Sources in Direct Reprogramming.
Front Bioeng Biotechnol
; 9: 658498, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33777923
10.
Assessment of the Effects of Altered Amyloid-Beta Clearance on Behavior following Repeat Closed-Head Brain Injury in Amyloid-Beta Precursor Protein Humanized Mice.
J Neurotrauma
; 38(5): 665-676, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33176547
11.
Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease.
J Neurosci
; 29(4): 1115-25, 2009 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19176820
12.
Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model.
Nat Neurosci
; 8(10): 1343-9, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16136043
13.
Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice.
BMC Neurosci
; 9: 109, 2008 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19014502
14.
Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides.
EMBO Mol Med
; 8(4): 328-45, 2016 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26902204
15.
Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.
J Neurosci
; 23(6): 1992-6, 2003 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12657655
16.
Neprilysin regulates amyloid Beta peptide levels.
J Mol Neurosci
; 22(1-2): 5-11, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-14742905
17.
Amyloid-beta and Alzheimer's disease: the role of neprilysin-2 in amyloid-beta clearance.
Front Aging Neurosci
; 6: 187, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25165447
18.
Identification and characterization of Aß peptide interactors in Alzheimer's disease by structural approaches.
Front Aging Neurosci
; 6: 265, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25346686
19.
Of mice and men: neurogenesis, cognition and Alzheimer's disease.
Front Aging Neurosci
; 5: 43, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23986699
20.
Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.
Neurobiol Aging
; 33(5): 1001.e1-6, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21531043