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J Pharm Pharm Sci ; 21(1): 73-93, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29510800

RESUMO

The microneedles technology has found applications in many health-related fields. For example, their application in drugs and vaccines delivery as well, as the determination of biomarkers, has been reported. They also have a place in the dermatology and cosmetic areas such as the treatment of wounds from burns, scars, acne, depigmentation, and alopecia will be shown. Microneedles are used in therapeutic applications and are manufactured using materials such as metal (steel, titanium, nickel), polymer (oly-glycolic acid (PGA), poly-lactide-co-glycolide acid (PLGA), poly-L-lactic acid (PLA), chitosan), glass, silicon, ceramic, carbohydrates (trehalose, sucrose, mannitol). Examples of application of microneedles and their advantages and disadvantages are discussed. This article is open to POST-PUBLICATION REVIEW. Registered readers (see "For Readers") may comment by clicking on ABSTRACT on the issue's contents page.


Assuntos
Cosméticos , Sistemas de Liberação de Medicamentos , Agulhas , Preparações Farmacêuticas/metabolismo , Pele/metabolismo , Absorção Fisiológica , Humanos , Preparações Farmacêuticas/química , Pele/química
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