Detalhe da pesquisa
1.
SomaMutDB: a database of somatic mutations in normal human tissues.
Nucleic Acids Res
; 50(D1): D1100-D1108, 2022 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34634815
2.
Aging: a sirtuin shake-up?
Cell
; 135(5): 797-8, 2008 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19041745
3.
Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan.
Proc Natl Acad Sci U S A
; 116(18): 9014-9019, 2019 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30992375
4.
Accurate identification of single-nucleotide variants in whole-genome-amplified single cells.
Nat Methods
; 14(5): 491-493, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28319112
5.
Quantitative detection of low-abundance somatic structural variants in normal cells by high-throughput sequencing.
Nat Methods
; 13(7): 584-6, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27271197
6.
Analyzing somatic mutations by single-cell whole-genome sequencing.
Nat Protoc
; 19(2): 487-516, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37996541
7.
Evidence for negative selection in human primary fibroblasts to tolerate high somatic mutation loads upon treatment with multiple low doses of N-ethyl-N-nitrosourea.
bioRxiv
; 2024 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38617356
8.
Negative Selection Allows DNA Mismatch Repair-Deficient Mouse Fibroblasts In Vitro to Tolerate High Levels of Somatic Mutations.
bioRxiv
; 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38766154
9.
Somatic mutation burden in relation to aging and functional life span: implications for cellular reprogramming and rejuvenation.
Curr Opin Genet Dev
; 83: 102132, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37931583
10.
Concurrent analysis of genome and transcriptome in one single cell.
Res Sq
; 2023 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37577506
11.
Female reproductive tract microbiome and early miscarriages.
APMIS
; 131(2): 61-76, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36511842
12.
Mitigating age-related somatic mutation burden.
Trends Mol Med
; 29(7): 530-540, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37121869
13.
Transcriptional profiling reveals ataxia telangiectasia mutated pathways regulate joint copper and arsenic toxicity for hepatic metalloplasia and anti-cancer therapies.
Life Sci
; 305: 120787, 2022 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35809665
14.
Single-molecule, quantitative detection of low-abundance somatic mutations by high-throughput sequencing.
Sci Adv
; 8(14): eabm3259, 2022 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35394831
15.
Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2 mutation carriers.
J Clin Invest
; 132(5)2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35025760
16.
Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking.
Nat Genet
; 54(4): 492-498, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35410377
17.
Maintenance of genome sequence integrity in long- and short-lived rodent species.
Sci Adv
; 7(44): eabj3284, 2021 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34705500
18.
Age-related telomere attrition causes aberrant gene expression in sub-telomeric regions.
Aging Cell
; 20(6): e13357, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34018656
19.
Genome instability, cancer and aging.
Biochim Biophys Acta
; 1790(10): 963-9, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19344750
20.
FOXO3a acts to suppress DNA double-strand break-induced mutations.
Aging Cell
; 19(9): e13184, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32720744