Detalhe da pesquisa
1.
Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate.
Mol Cell
; 84(3): 476-489.e10, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38211589
2.
Noncoding deletions reveal a gene that is critical for intestinal function.
Nature
; 571(7763): 107-111, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31217582
3.
Intravenous infusion of iPSC-derived neural precursor cells increases acid ß-glucosidase function in the brain and lessens the neuronopathic phenotype in a mouse model of Gaucher disease.
Hum Mol Genet
; 28(20): 3406-3421, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31373366
4.
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids.
Nature
; 516(7531): 400-4, 2014 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25363776
5.
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro.
Nature
; 470(7332): 105-9, 2011 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21151107
6.
Dynamic transcriptional and epigenomic reprogramming from pediatric nasal epithelial cells to induced pluripotent stem cells.
J Allergy Clin Immunol
; 135(1): 236-44, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25441642
7.
High-risk human papillomavirus E6 protein promotes reprogramming of Fanconi anemia patient cells through repression of p53 but does not allow for sustained growth of induced pluripotent stem cells.
J Virol
; 88(19): 11315-26, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25031356
8.
RB tumor suppressive function in response to xenobiotic hepatocarcinogens.
Am J Pathol
; 184(6): 1853-9, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24726645
9.
A review of protocols for brain organoids and applications for disease modeling.
STAR Protoc
; 4(1): 101860, 2023 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36566384
10.
iPSC-derived neural precursor cells engineering GBA1 recovers acid ß-glucosidase deficiency and diminishes α-synuclein and neuropathology.
Mol Ther Methods Clin Dev
; 29: 185-201, 2023 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37063480
11.
Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon.
Cell Stem Cell
; 30(11): 1434-1451.e9, 2023 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37922878
12.
RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage.
Gastroenterology
; 141(4): 1439-50, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21704587
13.
Aggregation of cryopreserved mid-hindgut endoderm for more reliable and reproducible hPSC-derived small intestinal organoid generation.
Stem Cell Reports
; 17(8): 1889-1902, 2022 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35905739
14.
Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency.
JHEP Rep
; 4(4): 100446, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35284810
15.
Unique impact of RB loss on hepatic proliferation: tumorigenic stresses uncover distinct pathways of cell cycle control.
J Biol Chem
; 285(2): 1089-96, 2010 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19887370
16.
Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells.
Gastroenterology
; 138(5): 1920-30, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20100483
17.
High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids.
Cells
; 10(12)2021 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34943927
18.
Converting human pluripotent stem cells into beta-cells: recent advances and future challenges.
Curr Opin Organ Transplant
; 15(1): 54-60, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19855279
19.
Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids.
Cell Metab
; 30(2): 374-384.e6, 2019 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31155493
20.
Repression of Ah receptor and induction of transforming growth factor-beta genes in DEN-induced mouse liver tumors.
Toxicology
; 246(2-3): 242-7, 2008 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-18282651