Detalhe da pesquisa
1.
Fluoromethylcyclopropylamine derivatives as potential in vivo toxicophores - A cautionary disclosure.
Bioorg Med Chem Lett
; 29(4): 560-562, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30616904
2.
Development and evaluation of 4-(pyrrolidin-3-yl)benzonitrile derivatives as inhibitors of lysine specific demethylase 1.
Bioorg Med Chem Lett
; 27(20): 4755-4759, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28927796
3.
Development of 5-hydroxypyrazole derivatives as reversible inhibitors of lysine specific demethylase 1.
Bioorg Med Chem Lett
; 27(14): 3190-3195, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28545974
4.
Reversible inhibitors of LSD1 as therapeutic agents in acute myeloid leukemia: clinical significance and progress to date.
Med Res Rev
; 35(3): 586-618, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25418875
5.
Catalytic aza-Wittig cyclizations for heteroaromatic synthesis.
Org Lett
; 10(12): 2589-91, 2008 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-18489173
6.
Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides.
J Med Chem
; 61(23): 10767-10792, 2018 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30403352
7.
Development of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1.
J Med Chem
; 60(19): 7984-7999, 2017 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28892629
8.
First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib.
ACS Chem Biol
; 11(11): 3179-3190, 2016 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27689388
9.
Toxoflavins and deazaflavins as the first reported selective small molecule inhibitors of tyrosyl-DNA phosphodiesterase II.
J Med Chem
; 56(16): 6352-70, 2013 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23859074