Detalhe da pesquisa
1.
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
Cell
; 184(20): 5089-5106.e21, 2021 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34555357
2.
Parkinson's disease-derived α-synuclein assemblies combined with chronic-type inflammatory cues promote a neurotoxic microglial phenotype.
J Neuroinflammation
; 21(1): 54, 2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38383421
3.
Altered vacuole membrane protein 1 (VMP1) expression is associated with increased NLRP3 inflammasome activation and mitochondrial dysfunction.
Inflamm Res
; 73(4): 563-580, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38411635
4.
Host oligodendrogliopathy and α-synuclein strains dictate disease severity in multiple system atrophy.
Brain
; 146(1): 237-251, 2023 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35170728
5.
Reactive astrocytes promote proteostasis in Huntington's disease through the JAK2-STAT3 pathway.
Brain
; 146(1): 149-166, 2023 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35298632
6.
The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model.
Mol Cell
; 62(2): 272-283, 2016 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27151442
7.
Synapses do not facilitate prion-like transfer of alpha-synuclein: a quantitative study in reconstructed unidirectional neural networks.
Cell Mol Life Sci
; 80(10): 284, 2023 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37688644
8.
Differential intracellular trafficking of extracellular vesicles in microglia and astrocytes.
Cell Mol Life Sci
; 80(7): 193, 2023 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37391572
9.
Detection of antibodies against the huntingtin protein in human plasma.
Cell Mol Life Sci
; 80(2): 45, 2023 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36651994
10.
Functional and neuropathological changes induced by injection of distinct alpha-synuclein strains: A pilot study in non-human primates.
Neurobiol Dis
; 180: 106086, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36933673
11.
Clustering of Tau fibrils impairs the synaptic composition of α3-Na+/K+-ATPase and AMPA receptors.
EMBO J
; 38(3)2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30630857
12.
Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct α-Synuclein Assemblies.
J Immunol
; 207(8): 2143-2154, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34507948
13.
Structural mapping techniques distinguish the surfaces of fibrillar 1N3R and 1N4R human tau.
J Biol Chem
; 297(5): 101252, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34592311
14.
The differential solvent exposure of N-terminal residues provides "fingerprints" of alpha-synuclein fibrillar polymorphs.
J Biol Chem
; 296: 100737, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33933456
15.
Disease Mechanisms of Multiple System Atrophy: What a Parallel Between the Form of Pasta and the Alpha-Synuclein Assemblies Involved in MSA and PD Tells Us.
Cerebellum
; 2022 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35657577
16.
Prion-like transmission of protein aggregates in neurodegenerative diseases.
Nat Rev Mol Cell Biol
; 11(4): 301-7, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20308987
17.
Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species.
J Biol Chem
; 295(28): 9676-9690, 2020 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32467226
18.
Distinct alpha-Synuclein species induced by seeding are selectively cleared by the Lysosome or the Proteasome in neuronally differentiated SH-SY5Y cells.
J Neurochem
; 156(6): 880-896, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32869336
19.
Glucose availability dictates the export of the soluble and prion forms of Sup35p via periplasmic or extracellular vesicles.
Mol Microbiol
; 114(2): 322-332, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32339313
20.
Crucial Role of FABP3 in αSyn-Induced Reduction of Septal GABAergic Neurons and Cognitive Decline in Mice.
Int J Mol Sci
; 22(1)2021 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33401521