Detalhe da pesquisa
1.
Rotenone Blocks the Glucocerebrosidase Enzyme and Induces the Accumulation of Lysosomes and Autophagolysosomes Independently of LRRK2 Kinase in HEK-293 Cells.
Int J Mol Sci
; 24(13)2023 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37445771
2.
PSEN1 E280A Cholinergic-like Neurons and Cerebral Spheroids Derived from Mesenchymal Stromal Cells and from Induced Pluripotent Stem Cells Are Neuropathologically Equivalent.
Int J Mol Sci
; 24(10)2023 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37240306
3.
TPEN exerts selective anti-leukemic efficacy in ex vivo drug-resistant childhood acute leukemia.
Biometals
; 34(1): 49-66, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33098492
4.
Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.
J Pineal Res
; 64(3)2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29247557
5.
Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function.
J Pineal Res
; 63(2)2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28423196
6.
Neuroprotective Effect of the LRRK2 Kinase Inhibitor PF-06447475 in Human Nerve-Like Differentiated Cells Exposed to Oxidative Stress Stimuli: Implications for Parkinson's Disease.
Neurochem Res
; 41(10): 2675-2692, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27394417
7.
Doxorubicin induces apoptosis in Jurkat cells by mitochondria-dependent and mitochondria-independent mechanisms under normoxic and hypoxic conditions.
Anticancer Drugs
; 26(6): 583-98, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25734830
8.
Rotenone Induces a Neuropathological Phenotype in Cholinergic-like Neurons Resembling Parkinson's Disease Dementia (PDD).
Neurotox Res
; 42(3): 28, 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38842585
9.
APOE3 Christchurch modulates ß-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer's cases.
Front Mol Neurosci
; 17: 1373568, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38571814
10.
Glucose starvation induces apoptosis in a model of acute T leukemia dependent on caspase-3 and apoptosis-inducing factor: a therapeutic strategy.
Nutr Cancer
; 65(1): 99-109, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23368919
11.
Neuroprotective Effect of Combined Treatment with Epigallocatechin 3-Gallate and Melatonin on Familial Alzheimer's Disease PSEN1 E280A Cerebral Spheroids Derived from Menstrual Mesenchymal Stromal Cells.
J Alzheimers Dis
; 2023 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36846998
12.
Cholinergic-like neurons and cerebral spheroids bearing the PSEN1 p.Ile416Thr variant mirror Alzheimer's disease neuropathology.
Sci Rep
; 13(1): 12833, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37553376
13.
Cannabidiol Protects Dopaminergic-like Neurons against Paraquat- and Maneb-Induced Cell Death through Safeguarding DJ-1CYS106 and Caspase 3 Independently of Cannabinoid Receptors: Relevance in Parkinson's Disease.
ACS Chem Neurosci
; 14(11): 2159-2171, 2023 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37220279
14.
Combinational treatment of TPEN and TPGS induces apoptosis in acute lymphoblastic and chronic myeloid leukemia cells in vitro and ex vivo.
Med Oncol
; 39(7): 109, 2022 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35578067
15.
Polycationic peptide R7-G-Aß25-35 selectively induces cell death in leukemia Jurkat T cells through speedy mitochondrial depolarization, and CASPASE-3 -independent mechanism.
Biochem Biophys Rep
; 31: 101300, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35755270
16.
TPEN/TPGS (T2) combo dramatically reduces Philadelphia chromosome-positive pro-lymphoblastic B leukemia in BALB/c mice.
Med Oncol
; 40(1): 15, 2022 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36352172
17.
(-)-Epigallocatechin-3-Gallate Diminishes Intra-and Extracellular Amyloid-Induced Cytotoxic Effects on Cholinergic-like Neurons from Familial Alzheimer's Disease PSEN1 E280A.
Biomolecules
; 11(12)2021 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34944489
18.
Multi-Target Effects of the Cannabinoid CP55940 on Familial Alzheimer's Disease PSEN1 E280A Cholinergic-Like Neurons: Role of CB1 Receptor.
J Alzheimers Dis
; 82(s1): S359-S378, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33252082
19.
Latent Tri-lineage Potential of Human Menstrual Blood-Derived Mesenchymal Stromal Cells Revealed by Specific In Vitro Culture Conditions.
Mol Neurobiol
; 58(10): 5194-5209, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34269964
20.
Cholinergic-like neurons carrying PSEN1 E280A mutation from familial Alzheimer's disease reveal intraneuronal sAPPß fragments accumulation, hyperphosphorylation of TAU, oxidative stress, apoptosis and Ca2+ dysregulation: Therapeutic implications.
PLoS One
; 15(5): e0221669, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32437347