RESUMO
Interleukine (IL-1alpha, IL-4) blood levels and lipid peroxidation--antioxidant agents were assessed in 98 patients with fractures of long tubular bones. Using the data, an algorithm was worked out, which permits prediction of septic complications with a high level of accuracy.
Assuntos
Fraturas Ósseas/cirurgia , Fraturas Fechadas/cirurgia , Interleucina-1alfa/sangue , Interleucina-4/sangue , Infecção da Ferida Cirúrgica/diagnóstico , Fraturas Ósseas/sangue , Fraturas Ósseas/classificação , Fraturas Fechadas/sangue , Fraturas Fechadas/classificação , Humanos , Peroxidação de Lipídeos , Prognóstico , Supuração/sangue , Supuração/diagnóstico , Infecção da Ferida Cirúrgica/sangueRESUMO
The serum levels of some indices of the LPO antioxidant system (dienic conjugates, antioxidative activity), cytokines (IL-1beta, TNF-alpha, IL-4) and the blood antiprotease system protein alpha2-macroglobulin were studied in 97 patients with closed long bone fractures. Based on the finding, a procedure was devised to evaluate the course of an inflammatory process in the early postoperative period, which predicted the development of pyoinflammatory complications at a stage of preclinical manifestations.