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We present a case of a 56-year-old female with rheumatoid arthritis (RA) who has been on methotrexate for 9 years and has been complaining of high-grade fever for the past 1 month with no localizing signs and symptoms. She was thoroughly evaluated before being labeled as pyrexia of unknown origin. Histoplasmosis was suspected after bone marrow aspiration smear examination. The presence of histoplasma antigen in the urine confirmed our diagnosis. Fever responded after 2 weeks of liposomal amphotericin B and patient discharged in stable condition on tablet itraconazole.
Assuntos
Anfotericina B , Artrite Reumatoide , Febre de Causa Desconhecida , Histoplasmose , Humanos , Histoplasmose/diagnóstico , Histoplasmose/complicações , Histoplasmose/tratamento farmacológico , Artrite Reumatoide/complicações , Artrite Reumatoide/tratamento farmacológico , Artrite Reumatoide/diagnóstico , Feminino , Pessoa de Meia-Idade , Febre de Causa Desconhecida/etiologia , Febre de Causa Desconhecida/diagnóstico , Anfotericina B/uso terapêutico , Antifúngicos/uso terapêutico , Histoplasma/isolamento & purificação , Itraconazol/uso terapêuticoRESUMO
The concept of fuzzy set, intuitionistic set, and mediative fuzzy set as a generalization of a crisp set have been introduced in many real-life applications. The concept of crisp relation between elements of sets can be extended to fuzzy relations. Extended relations will be considered as relations on fuzzy sets. In this work, we developed the concept of mediative fuzzy relation and meditative fuzzy projection in the context of fuzzy relation and fuzzy projection. We extended the basic operations of fuzzy projection into intuitionistic fuzzy projection and then in the mediative fuzzy projection. We have shown the credibility and impact of mediative index factor involves in the mediative fuzzy projection in context of prediction work in relation to the proposed model. Further, we applied the mediative fuzzy projection in the medical diagnosis in post-COVID-19 patients. The obtained results have also been discussed with their geometrical representation.
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This paper presents a model based on mediative fuzzy logic in this COVID-19 pandemic. COVID-19 (novel coronavirus respiratory disease) has become a pandemic now and the whole world has been affected by this disease. Different methodologies and many prediction techniques based on various models have been developed so far. In the present article, we have developed a mediative fuzzy correlation technique based on the parameters for COVID-19 patients from different parts of India. The proposed mediative fuzzy correlation technique provides the relation between the increments of COVID-19 positive patients in terms of the passage of increment with respect to time. The peaks of infected cases in connection with the other condition are estimated from the available data. The mediative fuzzy logic mathematical model can be utilized to find a good fit or a contradictory model for any pandemic model. The proposed approach to the prediction in COVID-19 based on mediative fuzzy logic has produced promising results for the continuous contradictory prediction in India.
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In this paper, we have considered a mathematical model that deals with the effectiveness of the measures that may be helpful for reducing the spread of the COVID-19 virus in the society. Here we have illustrated the importance of lock down in controlling and maintaining the spread of the COVID-19 virus. The impact of the virus on the susceptible population has been considered in the model. Also, we have taken into account the susceptible population, which by taking preventive measures viz., by having strong immunity, maintaining social distancing, wearing PPE kits and masks etc., is able to reduce the possibility of getting infected from the virus. Local as well as global stability of the equilibrium points of the model have been studied using Lyapunov function and the geometrical approach techniques. Basic reproduction number has also been obtained by using the next generation matrix. To show the effectiveness of the model, different cases obtained by varying the parameters involved in the model have been considered. A comparison between the actual number of infected cases in India and that obtained by the proposed model, showing the effectiveness of the proposed model, has also been carried out.
Assuntos
COVID-19 , Número Básico de Reprodução , COVID-19/epidemiologia , COVID-19/prevenção & controle , Controle de Doenças Transmissíveis/métodos , Humanos , Modelos Teóricos , SARS-CoV-2RESUMO
In this paper, we have mathematically analyzed a within-host model of SARS-CoV-2 which is used by Li et al. in the paper "The within-host viral kinetics of SARS-CoV-2" published in (Math. Biosci. Eng. 17(4):2853-2861, 2020). Important properties of the model, like nonnegativity of solutions and their boundedness, are established. Also, we have calculated the basic reproduction number which is an important parameter in the infection models. From stability analysis of the model, it is found that stability of the biologically feasible steady states are determined by the basic reproduction number ( χ 0 ) . Numerical simulations are done in order to substantiate analytical results. A biological implication from this study is that a COVID-19 patient with less than one basic reproduction ratio can automatically recover from the infection.
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In the present paper, we introduce the Chlodowsky variant of [Formula: see text] Bernstein-Stancu-Schurer operators which is a generalization of [Formula: see text] Bernstein-Stancu-Schurer operators. We also discuss its Korovkin-type approximation properties and rate of convergence.
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In this paper, we introduce a system of generalized implicit variational inclusions which consists of three variational inclusions. We design an iterative algorithm with error terms based on relaxed resolvent operator due to Ahmad et al. (Stat Optim Inf Comput 4:183-193, 2016) for approximating the solution of our system. The convergence of the iterative sequences generated by the iterative algorithm is also discussed. An example is given which satisfy all the conditions of our main result.