Detalhe da pesquisa
1.
Salicylates enhance CRM1 inhibitor antitumor activity by induction of S-phase arrest and impairment of DNA-damage repair.
Blood
; 137(4): 513-523, 2021 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33507295
2.
Central Nervous System Delivery of the Catalytic Subunit of DNA-Dependent Protein Kinase Inhibitor Peposertib as Radiosensitizer for Brain Metastases.
J Pharmacol Exp Ther
; 381(3): 217-228, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35370138
3.
Factors Influencing Luciferase-Based Bioluminescent Imaging in Preclinical Models of Brain Tumor.
Drug Metab Dispos
; 50(3): 277-286, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34887255
4.
Automatic 3D Nonlinear Registration of Mass Spectrometry Imaging and Magnetic Resonance Imaging Data.
Anal Chem
; 91(9): 6206-6216, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30932478
5.
Brain Distribution and Active Efflux of Three panRAF Inhibitors: Considerations in the Treatment of Melanoma Brain Metastases.
J Pharmacol Exp Ther
; 368(3): 446-461, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30622172
6.
Inhibiting DNA-PKCS radiosensitizes human osteosarcoma cells.
Biochem Biophys Res Commun
; 486(2): 307-313, 2017 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28300555
7.
Heterogeneous Binding and Central Nervous System Distribution of the Multitargeted Kinase Inhibitor Ponatinib Restrict Orthotopic Efficacy in a Patient-Derived Xenograft Model of Glioblastoma.
J Pharmacol Exp Ther
; 363(2): 136-147, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28847917
8.
Delivery versus Potency in Treating Brain Tumors: BI-907828, a MDM2-p53 Antagonist with Limited BBB Penetration but Significant In Vivo Efficacy in Glioblastoma.
Mol Cancer Ther
; 23(1): 47-55, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37828724
9.
Differential Distribution of the DNA-PKcs Inhibitor Peposertib Selectively Radiosensitizes Patient-derived Melanoma Brain Metastasis Xenografts.
Mol Cancer Ther
; 23(5): 662-671, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38224566
10.
WSD-0922, a novel brain-penetrant inhibitor of epidermal growth factor receptor, promotes survival in glioblastoma mouse models.
Neurooncol Adv
; 5(1): vdad066, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37324218
11.
ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells.
J Neurooncol
; 110(3): 349-57, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23054561
12.
RBBP4-p300 axis modulates expression of genes essential for cell survival and is a potential target for therapy in glioblastoma.
Neuro Oncol
; 24(8): 1261-1272, 2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35231103
13.
Preclinical modeling in glioblastoma patient-derived xenograft (GBM PDX) xenografts to guide clinical development of lisavanbulin-a novel tumor checkpoint controller targeting microtubules.
Neuro Oncol
; 24(3): 384-395, 2022 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34232318
14.
Multimodal platform for assessing drug distribution and response in clinical trials.
Neuro Oncol
; 24(1): 64-77, 2022 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34383057
15.
Convection enhanced delivery of EGFR targeting antibody-drug conjugates Serclutamab talirine and Depatux-M in glioblastoma patient-derived xenografts.
Neurooncol Adv
; 4(1): vdac130, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36071925
16.
Quantitative Analysis of Tyrosine Phosphorylation from FFPE Tissues Reveals Patient-Specific Signaling Networks.
Cancer Res
; 81(14): 3930-3941, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34016623
17.
Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities.
Cell Rep
; 37(8): 110054, 2021 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34818553
18.
In Vivo Efficacy of Tesevatinib in EGFR-Amplified Patient-Derived Xenograft Glioblastoma Models May Be Limited by Tissue Binding and Compensatory Signaling.
Mol Cancer Ther
; 20(6): 1009-1018, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33785646
19.
Heterogeneous delivery across the blood-brain barrier limits the efficacy of an EGFR-targeting antibody drug conjugate in glioblastoma.
Neuro Oncol
; 23(12): 2042-2053, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34050676
20.
Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines.
Mol Cancer Ther
; 8(2): 407-14, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19174557