Detalhe da pesquisa
1.
Shapeshifting bullvalene-linked vancomycin dimers as effective antibiotics against multidrug-resistant gram-positive bacteria.
Proc Natl Acad Sci U S A
; 120(15): e2208737120, 2023 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37011186
2.
Diversity oriented clicking delivers ß-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors.
Proc Natl Acad Sci U S A
; 119(37): e2208540119, 2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36070343
3.
Ethene-1,1-disulfonyl Difluoride (EDSF) for SuFEx Click Chemistry: Synthesis of SuFExable 1,1-Bissulfonylfluoride Substituted Cyclobutene Hubs.
Angew Chem Int Ed Engl
; 62(30): e202303916, 2023 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37224463
4.
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase.
Proc Natl Acad Sci U S A
; 116(38): 18808-18814, 2019 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31484779
5.
Accelerated SuFEx Click Chemistry For Modular Synthesis.
Angew Chem Int Ed Engl
; 61(4): e202112375, 2022 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34755436
6.
Mechanism of intersubunit ketosynthase-dehydratase interaction in polyketide synthases.
Nat Chem Biol
; 14(3): 270-275, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29309054
7.
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2-Substituted-Alkynyl-1-Sulfonyl Fluoride (SASF) Hubs.
Angew Chem Int Ed Engl
; 59(30): 12460-12469, 2020 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32301265
8.
Metal-Free Synthesis of Functional 1-Substituted-1,2,3-Triazoles from Ethenesulfonyl Fluoride and Organic Azides.
Angew Chem Int Ed Engl
; 59(3): 1181-1186, 2020 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31709653
9.
Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4 )-Derived Connective Hubs for Bioconjugation to DNA and Proteins.
Angew Chem Int Ed Engl
; 58(24): 8029-8033, 2019 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30998840
10.
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides.
Angew Chem Int Ed Engl
; 58(14): 4552-4556, 2019 03 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30740848
11.
Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms.
Chemistry
; 24(41): 10550-10556, 2018 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29949211
12.
Modification of Carbon Fibre Surfaces by Sulfur-Fluoride Exchange Click Chemistry.
Chemphyschem
; 2018 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30253016
13.
SuFEx Chemistry of Thionyl Tetrafluoride (SOF4 ) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates.
Angew Chem Int Ed Engl
; 57(7): 1939-1943, 2018 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29314580
14.
Reengineering Antibiotics to Combat Bacterial Resistance: Click Chemistry [1,2,3]-Triazole Vancomycin Dimers with Potent Activity against MRSA and VRE.
Chemistry
; 23(1): 79-83, 2017 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27747932
15.
Sulfur-Fluoride Exchange (SuFEx)-Mediated Synthesis of Sterically Hindered and Electron-Deficient Secondary and Tertiary Amides via Acyl Fluoride Intermediates.
Chemistry
; 23(42): 9990-9995, 2017 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28612408
16.
Correction: The growing applications of click chemistry.
Chem Soc Rev
; 45(24): 6888, 2016 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27809327
17.
Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched From An SOF4 Hub.
Angew Chem Int Ed Engl
; 56(11): 2903-2908, 2017 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28165188
18.
Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein.
Angew Chem Int Ed Engl
; 56(47): 14873-14877, 2017 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28960650
19.
Chemoselective Synthesis of Polysubstituted Pyridines from Heteroaryl Fluorosulfates.
Chemistry
; 22(16): 5692-7, 2016 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26990693
20.
Horner-Wadsworth-Emmons approach to piperlongumine analogues with potent anti-cancer activity.
Org Biomol Chem
; 14(31): 7585-93, 2016 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27443386