Detalhe da pesquisa
1.
Sulforaphane is Synergistic with CB-5083 and Inhibits Colony Formation of CB-5083-Resistant HCT116 Cells.
ChemMedChem
; 17(11): e202200030, 2022 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35451199
2.
Comparative Oncology Assessment of a Novel Inhibitor of Valosin-Containing Protein in Tumor-Bearing Dogs.
Mol Cancer Ther
; 21(10): 1510-1523, 2022 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35876604
3.
Structure-based design of novel human Pin1 inhibitors (I).
Bioorg Med Chem Lett
; 19(19): 5613-6, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19729306
4.
An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanisms.
Cancer Res
; 67(9): 4408-17, 2007 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17483355
5.
Structure activity relationships of quinoline-containing c-Met inhibitors.
Eur J Med Chem
; 43(6): 1321-9, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17964000
6.
Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma.
Mol Cancer Ther
; 6(12 Pt 1): 3314-22, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18089725
7.
2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition.
Science
; 351(6275): 871-5, 2016 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26822609
8.
Structure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).
J Med Chem
; 54(18): 6342-63, 2011 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21812414
9.
Phase 0 clinical trials: conceptions and misconceptions.
Cancer J
; 14(3): 133-7, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18536551
10.
Identification and characterization of a novel and functional murine Pin1 isoform.
Biochem Biophys Res Commun
; 359(3): 529-35, 2007 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-17548053