Assessing the energy trap of industrial agriculture in North America and Europe: 82 balances from 1830 to 2012.

Early energy analyses of agriculture revealed that behind higher labor and land productivity of industrial farming, there was a decrease in energy returns on energy (EROI) invested, in comparison to more traditional organic agricultural systems. Studies on recent trends show that efficiency gains in production and use of inputs have again somewhat improved energy returns. However, most of these agricultural energy studies have focused only on external inputs at the crop level, concealing the important role of internal biomass flows that livestock and forestry recirculate within agroecosystems. Here, we synthesize the results of 82 farm systems in North America and Europe from 1830 to 2012 that for the first time show the changing energy profiles of agroecosystems, including livestock and forestry, with a multi-EROI approach that accounts for the energy returns on external inputs, on internal biomass reuses, and on all inputs invested. With this historical circular bioeconomic approach, we found a general trend towards much lower external returns, little or no increases in internal returns, and almost no improvement in total returns. This "energy trap" was driven by shifts towards a growing dependence of crop production on fossil-fueled external inputs, much more intensive livestock production based on feed grains, less forestry, and a structural disintegration of agroecosystem components by increasingly linear industrial farm managements. We conclude that overcoming the energy trap requires nature-based solutions to reduce current dependence on fossil-fueled external industrial inputs and increase the circularity and complexity of agroecosystems to provide healthier diets with less animal products. Supplementary Information: The online version contains supplementary material available at 10.1007/s13593-023-00925-5.

Transcending capitalism growth strategies for biodiversity conservation.

The unlimited economic growth that fuels capitalism's metabolism has profoundly transformed a large portion of Earth. The resulting environmental destruction has led to an unprecedented rate of biodiversity loss. Following large-scale losses of habitats and species, it was recognized that biodiversity is crucial to maintaining functional ecosystems. We sought to continue the debate on the contradictions between economic growth and biodiversity in the conservation science literature and thus invite scholars to engage in reversing the biodiversity crisis through acknowledging the impacts of economic growth. In the 1970s, a global agenda was set to develop different milestones related to sustainable development, including green-blue economic growth, which despite not specifically addressing biodiversity reinforced the idea that economic development based on profit is compatible with the planet's ecology. Only after biodiversity loss captured the attention of environmental sciences researchers in the early 2000s was a global biodiversity agenda implemented. The agenda highlights biodiversity conservation as a major international challenge and recognizes that the main drivers of biodiversity loss derive from economic activities. The post-2000 biodiversity agendas, including the 2030 Agenda for Sustainable Development and the post-2020 Convention on Biological Diversity Global Strategy Framework, do not consider the negative impacts of growth-oriented strategies on biodiversity. As a result, global biodiversity conservation priorities are governed by the economic value of biodiversity and its assumed contribution to people's welfare. A large body of empirical evidence shows that unlimited economic growth is the main driver of biodiversity loss in the Anthropocene; thus, we strongly argue for sustainable degrowth and a fundamental shift in societal values. An equitable downscaling of the physical economy can improve ecological conditions, thus reducing biodiversity loss and consequently enhancing human well-being.

Trascendiendo las Estrategias de Crecimiento Capitalista para la Conservación de la Biodiversidad Resumen El crecimiento económico ilimitado que alimenta el metabolismo del capitalismo ha transformado profundamente una gran parte del planeta Tierra. La destrucción ambiental resultante ha traído como consecuencia una tasa sin precedentes de pérdida de diversidad biológica. Después de la pérdida a gran escala de hábitats y especies, se reconoció que la biodiversidad es crucial para mantener el funcionamiento de los ecosistemas. En este articulo buscamos seguir con el debate sobre las contradicciones entre el crecimiento económico y la biodiversidad en la literatura de las ciencias de la conservación y así invitar a los académicos a participar en la reducción de la crisis de biodiversidad dando a conocer los impactos del crecimiento económico. En la década de 1970, se estableció una agenda global para desarrollar diferentes metas relacionadas con el desarrollo sustentable, incluyendo el crecimiento económico verde y azul, la cual a pesar de no mencionar específicamente la biodiversidad reforzó la idea de que el desarrollo económico basado en ganancias es compatible con la ecología del planeta. Fue solamente después de que la pérdida de biodiversidad captó la atención de los investigadores de las ciencias ambientales a principios de la década de los 2000 que se implementó una agenda para la diversidad biológica. La agenda resalta que la conservación de la biodiversidad es un gran reto internacional y reconoce que las pincipales causas de la pérdida de la diversidad biológica derivan de las actividades económicas. Las agendas para la biodiversidad creadas después del 2000, incluyendo la Agenda 2030 para el Desarrollo Sustentable y el Marco de Trabajo de la Estrategia Mundial de la Convención sobre la Diversidad Biológica posterior a 2020, no consideran los impactos negativos de las estrategias para la biodiversidad orientadas por el crecimiento. Como resultado, las prioridades de la conservación mundial de la biodiversidad están gobernadas por el valor económico de la biodiversidad y la supuesta contribución que tiene para el bienestar de las personas. Una gran cantidad de evidencia empírica muestra que el crecimiento económico ilimitado es el principal conductor de la pérdida de diversidad biológica en el Antropoceno; por lo tanto, abogamos fuertemente por un decrecimiento sustentable y un cambio fundamental en los valores sociales. Una reducción equitativa de la economía física puede mejorar las condiciones ecológicas, reduciendo así la pérdida de biodiversidad y mejorando como consecuencia el bienestar humano.

Efficacy of omega-3 highly unsaturated fatty acids in the treatment of depression.

BACKGROUND: Trials evaluating efficacy of omega-3 highly unsaturated fatty acids (HUFAs) in major depressive disorder report discrepant findings. AIMS: To establish the reasons underlying inconsistent findings among randomised controlled trials (RCTs) of omega-3 HUFAs for depression and to assess implications for further trials. METHOD: A systematic bibliographic search of double-blind RCTs was conducted between January 1980 and July 2014 and an exploratory hypothesis-testing meta-analysis performed in 35 RCTs including 6665 participants receiving omega-3 HUFAs and 4373 participants receiving placebo. RESULTS: Among participants with diagnosed depression, eicosapentaenoic acid (EPA)-predominant formulations (>50% EPA) demonstrated clinical benefits compared with placebo (Hedge's G = 0.61, P<0.001) whereas docosahexaenoic acid (DHA)-predominant formulations (>50% DHA) did not. EPA failed to prevent depressive symptoms among populations not diagnosed for depression. CONCLUSIONS: Further RCTs should be conducted on study populations with diagnosed or clinically significant depression of adequate duration using EPA-predominant omega-3 HUFA formulations.

Clozapine-induced stuttering: an estimate of prevalence in the west of Ireland.

OBJECTIVES: Clozapine is the most effective treatment available for treatment-resistant schizophrenia; however, it is also associated with a large array of adverse effects that limits its tolerability. A number of previous case reports have noted an association between clozapine and stuttering, however the rate of this possible adverse effect is yet to be established. METHODS: In this paper, we present six cases of patients treated with clozapine who developed stuttering. RESULTS: Clozapine was associated with stuttering in 0.92% of individuals treated with clozapine in the region. Clozapine-induced stuttering was associated with an increase in treatment dose or with dose titration at initiation of clozapine in five individuals, with dose reduction or slower dose titration associated with a cessation of stuttering in these cases. CONCLUSIONS: This is the largest case series to date examining clozapine-induced stuttering and indicates that clozapine-induced stuttering is a relatively common adverse effect that can be managed by a slower titration of clozapine dosage or a modest reduction in dose in most cases.

Childhood trauma levels in individuals attending adult mental health services: An evaluation of clinical records and structured measurement of childhood trauma.

Despite an increased awareness regarding the prevalence and impact of childhood trauma, especially childhood sexual abuse (CSA), few studies examine the clinical reporting of such childhood experiences. This study compared the prevalence of childhood trauma recorded in individual's clinical notes to those ascertained with a structured validated questionnaire, examined which forms of childhood trauma were less likely to be reported to the treating mental health team and established which demographic or clinical factors were associated with reporting of childhood trauma. The prevalence of childhood trauma was ascertained using both the Childhood Trauma Questionnaire (CTQ) and a lifetime retrospective clinical note review in 129 individuals attending a general adult mental health service. Individuals were evaluated for the presence of mental health disorders, impulsivity, symptom severity and disability. Using the CTQ, childhood trauma was noted in 77% of individuals and recorded in 38% of individual's clinical notes (p<0.001). The greatest differences between CTQ reporting and clinical note documentation were noted for emotional neglect (62% versus 13.2%), physical neglect (48.1% versus 5.4%) and CSA (24.8% versus 8.5%). Childhood trauma was associated with increased psychopathology and greater symptom severity, and was particularly prevalent for individuals with personality disorders. This study demonstrated high rates of childhood trauma amongst adults attending a general adult mental health service. Furthermore, we demonstrated high rates of either non-enquiry from mental health professionals and/or high rates of non-documentation of childhood trauma by mental health professionals. Given the disparity between reporting of childhood trauma in clinical notes and findings with the CTQ, the use of a standardised questionnaire for the assessment of childhood trauma should be considered when performing a comprehensive mental health history.

Analysis of prescribing practices in an acute psychiatric ward.

OBJECTIVES: Prescription writing is a basic clinical skill for all doctors; however, errors in prescriptions are frequent and can result in significant harm to patients both from sub-therapeutic dosages and from over prescribing. This study examines the prescribing practices of 'as required' medications in an acute psychiatric inpatient unit attached to a university teaching hospital. METHOD: A clinical audit was conducted to examine both prescribing practices of 'as required' medication and recording of 'as required' medication in nursing notes. A series of educational interventions were undertaken in an attempt to improve prescribing practices in relation to 'as required' medication and two further audits were completed to assess any change in practice and whether such changes were sustained. RESULTS: Psycho-education led to an improvement in a number of prescribing practices, including increased generic prescribing, improved documentation of indications for medication administration and increased writing of medication dosages in acceptable abbreviations. These benefits were maintained four months after the education interventions. Rates of documenting the frequency of medication correctly and recording the administration of medication in nursing notes remained low. CONCLUSION: Our audit cycle clearly demonstrates that education can ameliorate prescribing practices and these improvements were maintained four months after education was delivered. However some aspects of prescribing practice remained deficient, and more focused educational interventions are required in these areas.

Has the Mental Health Act 2001 altered the clinical profile of involuntary admissions?

OBJECTIVES: To assess whether transition from the Mental Treatment Act (MTA), 1945 to the Mental Health Act (MHA), 2001 has had any impact on the clinical profile of patients in the West Galway Mental Health Services who are admitted on an involuntary basis. METHODS: Data were collected from clinical records in relation to all those individuals residing in the West Galway Mental Health Services who were admitted involuntarily in the 12 months prior to and subsequent to the introduction of the MHA 2001. RESULTS: A total of 175 individuals were included in this study (n = 91 - MTA 1945; and n = 84 - MHA 2001). No significant differences were found between the two groups in relation to demographic data, rates of involuntary detention or duration of involuntary detention. The applicant was less likely to be a family member under the MHA 2001 (54%) than the MTA 1945 (85%). CONCLUSIONS: Transition from the MTA 1945 to the MHA 2001 has had minimal impact on the admission rates, clinical profile or duration of detention of patients admitted involuntarily in the West Galway Mental Health Services.

Clozapine induced stuttering.

We describe two cases reports, demonstrating an association between clozapine treatment and stuttering. Stuttering in both cases was dose-related and a significant improvement was noted when the dose of clozapine was reduced.