Detalhe da pesquisa
1.
Age-induced accumulation of methylmalonic acid promotes tumour progression.
Nature
; 585(7824): 283-287, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32814897
2.
An affinity tool for the isolation of endogenous active mTORC1 from various cellular sources.
J Biol Chem
; 299(5): 104644, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36965617
3.
Prolonged deprivation of arginine or leucine induces PI3K/Akt-dependent reactivation of mTORC1.
J Biol Chem
; 298(6): 102030, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35577075
4.
Regulation of GSK3 cellular location by FRAT modulates mTORC1-dependent cell growth and sensitivity to rapamycin.
Proc Natl Acad Sci U S A
; 116(39): 19523-19529, 2019 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31492813
5.
Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis.
Blood
; 131(15): 1712-1719, 2018 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29339402
6.
Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms.
Proc Natl Acad Sci U S A
; 108(46): 18814-9, 2011 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22065781
7.
Balancing lysosome abundance in health and disease.
Nat Cell Biol
; 25(9): 1254-1264, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37580388
8.
Altered propionate metabolism contributes to tumour progression and aggressiveness.
Nat Metab
; 4(4): 435-443, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35361954
9.
Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability.
Nat Commun
; 11(1): 1416, 2020 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32184389
10.
Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization.
Cancer Cell
; 36(4): 402-417.e13, 2019 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31564638
11.
Notch signaling promotes a HIF2α-driven hypoxic response in multiple tumor cell types.
Oncogene
; 37(46): 6083-6095, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29993038