Detalhe da pesquisa
1.
Targeting Gαi2 in neutrophils protects from myocardial ischemia reperfusion injury.
Basic Res Cardiol
; 2024 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38811421
2.
An inactivating human TRPC6 channel mutation without focal segmental glomerulosclerosis.
Cell Mol Life Sci
; 80(9): 265, 2023 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37615749
3.
Analysis of hyperforin (St. John's wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugs.
Mol Psychiatry
; 27(12): 5070-5085, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36224261
4.
Requirement of Na+/H+ Exchanger NHE1 for Vasopressin-Induced Osteogenic Signaling and Calcification in Human Aortic Smooth Muscle Cells.
Kidney Blood Press Res
; 47(6): 399-409, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35339998
5.
In Vivo Inhibition of TRPC6 by SH045 Attenuates Renal Fibrosis in a New Zealand Obese (NZO) Mouse Model of Metabolic Syndrome.
Int J Mol Sci
; 23(12)2022 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35743312
6.
Effect of MgCl2 and GdCl3 on ORAI1 Expression and Store-Operated Ca2+ Entry in Megakaryocytes.
Int J Mol Sci
; 22(7)2021 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33804889
7.
A single discrete Rab5-binding site in phosphoinositide 3-kinase ß is required for tumor cell invasion.
J Biol Chem
; 294(12): 4621-4633, 2019 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30659094
8.
Stimulation of ORAI1 expression, store-operated Ca2+ entry, and osteogenic signaling by high glucose exposure of human aortic smooth muscle cells.
Pflugers Arch
; 472(8): 1093-1102, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32556706
9.
Reversal of phosphate-induced ORAI1 expression, store-operated Ca2+ entry and osteogenic signaling by MgCl2 in human aortic smooth muscle cells.
Biochem Biophys Res Commun
; 523(1): 18-24, 2020 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31831178
10.
Salmonella Typhimurium effector SseI inhibits chemotaxis and increases host cell survival by deamidation of heterotrimeric Gi proteins.
PLoS Pathog
; 14(8): e1007248, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30102745
11.
Acid sphingomyelinase - a regulator of canonical transient receptor potential channel 6 (TRPC6) activity.
J Neurochem
; 150(6): 678-690, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31310676
12.
Renal Fibrosis, Immune Cell Infiltration and Changes of TRPC Channel Expression after Unilateral Ureteral Obstruction in Trpc6-/- Mice.
Cell Physiol Biochem
; 52(6): 1484-1502, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31099508
13.
Diabetic lung disease: fact or fiction?
Rev Endocr Metab Disord
; 20(3): 303-319, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31637580
14.
Gαi Proteins are Indispensable for Hearing.
Cell Physiol Biochem
; 47(4): 1509-1532, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29940568
15.
Rac1-stimulated macropinocytosis enhances Gßγ activation of PI3Kß.
Biochem J
; 474(23): 3903-3914, 2017 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29046393
16.
Platelet Gi protein Gαi2 is an essential mediator of thrombo-inflammatory organ damage in mice.
Proc Natl Acad Sci U S A
; 112(20): 6491-6, 2015 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25944935
17.
Deficiency of PI3-Kinase catalytic isoforms p110γ and p110δ in mice enhances the IL-17/G-CSF axis and induces neutrophilia.
Cell Commun Signal
; 15(1): 28, 2017 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28724384
18.
p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase.
J Biol Chem
; 290(48): 28915-31, 2015 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26438819
19.
Different inhibition of Gßγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gßγ-dependent regulator of PI3Kγ enzymatic activity.
Biochem J
; 469(1): 59-69, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26173259
20.
Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs).
Proc Natl Acad Sci U S A
; 110(47): 18862-7, 2013 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24190998