Detalhe da pesquisa
1.
Characterization of the dehydrogenase-reductase DHRS2 and its involvement in histone deacetylase inhibition in urological malignancies.
Exp Cell Res
; 439(1): 114055, 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38704080
2.
Genome-scale CRISPR screen reveals neddylation to contribute to cisplatin resistance of testicular germ cell tumours.
Br J Cancer
; 128(12): 2270-2282, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37024667
3.
Characterizing the mutational burden, DNA methylation landscape, and proteome of germ cell tumor-related somatic-type malignancies to identify the tissue-of-origin, mechanisms of therapy resistance, and druggable targets.
Br J Cancer
; 129(10): 1580-1589, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37726478
4.
Targeting CLDN6 in germ cell tumors by an antibody-drug-conjugate and studying therapy resistance of yolk-sac tumors to identify and screen specific therapeutic options.
Mol Med
; 29(1): 40, 2023 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36991316
5.
Updating germ cell tumour pathogenesis - the ability of seminomas for FOXA2-driven extra-embryonic differentiation.
Histopathology
; 83(3): 477-481, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37265221
6.
Primary mediastinal germ cell tumours: an immunohistochemical and molecular diagnostic approach.
Histopathology
; 80(2): 381-396, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34506648
7.
The pioneer and differentiation factor FOXA2 is a key driver of yolk-sac tumour formation and a new biomarker for paediatric and adult yolk-sac tumours.
J Cell Mol Med
; 25(3): 1394-1405, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33448076
8.
The detection of isochromosome i(12p) in malignant germ cell tumours and tumours with somatic malignant transformation by the use of quantitative real-time polymerase chain reaction.
Histopathology
; 78(4): 593-606, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32970854
9.
Unique and redundant roles of SOX2 and SOX17 in regulating the germ cell tumor fate.
Int J Cancer
; 146(6): 1592-1605, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31583686
10.
CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms.
Br J Cancer
; 123(3): 378-391, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32418994
11.
Deciphering the molecular effects of romidepsin on germ cell tumours: DHRS2 is involved in cell cycle arrest but not apoptosis or induction of romidepsin effectors.
J Cell Mol Med
; 23(1): 670-679, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30460772
12.
Tpbpa-Cre-mediated deletion of TFAP2C leads to deregulation of Cdkn1a, Akt1 and the ERK pathway, causing placental growth arrest.
Development
; 143(5): 787-98, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26811378
13.
Brentuximab vedotin exerts profound antiproliferative and pro-apoptotic efficacy in CD30-positive as well as cocultured CD30-negative germ cell tumour cell lines.
J Cell Mol Med
; 22(1): 568-575, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28941150
14.
BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma.
PLoS Genet
; 11(7): e1005415, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26226633
15.
The plasticity of germ cell cancers and its dependence on the cellular microenvironment.
J Cell Mol Med
; 21(8): 1463-1467, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28244655
16.
The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours in vitro and in vivo.
J Cell Mol Med
; 21(7): 1300-1314, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28026145
17.
Special Issue on Testis Cancer.
World J Urol
; 40(2): 305-306, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35226139
18.
The cancer/testis-antigen PRAME supports the pluripotency network and represses somatic and germ cell differentiation programs in seminomas.
Br J Cancer
; 115(4): 454-64, 2016 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27441500
19.
Elucidating human male germ cell development by studying germ cell cancer.
Reproduction
; 152(4): R101-13, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27512122
20.
Assessing the risk to develop a growing teratoma syndrome based on molecular and epigenetic subtyping as well as novel secreted biomarkers.
Cancer Lett
; 585: 216673, 2024 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38296184