RESUMO
Metabolic syndrome (MetS) being a risk factor for many vascular pathologic processes is associated with cognitive dysfunction with vascular genesis. Objective - to study the relationship between clinical and metabolic indicators and the presence of cognitive dysfunction in persons with MetS. A transverse study was conducted in the Turkestan region of Southern Kazakhstan during which a general clinical, laboratory examination and evaluation of cognitive function was performed in 639 patients. To assess the relationship between the MetS, its individual components and cognitive function with Mini Mental State Examination test (MMSE) multinominal logistic regression analysis was used. According to the MMSE test, signs of cognitive impairment were revealed in 4.1% of the examined. A statistically significant positive association was found between the chances of having cognitive impairment andMetS, systolic hypertension, diastolic hypertension, hypercholesterolemia, hyperglycaemia. Our results showed that the components of MetS correlate with cognitive impairment. Further research should be directed towards determining the impact of early detection and treatment of metabolic syndrome on cognitive ability.
Assuntos
Disfunção Cognitiva/epidemiologia , Hipercolesterolemia/epidemiologia , Hiperglicemia/epidemiologia , Hipertensão/epidemiologia , Síndrome Metabólica/epidemiologia , Adulto , Idoso , Disfunção Cognitiva/diagnóstico , Disfunção Cognitiva/fisiopatologia , Comorbidade , Estudos Transversais , Feminino , Humanos , Hipercolesterolemia/diagnóstico , Hipercolesterolemia/fisiopatologia , Hiperglicemia/diagnóstico , Hiperglicemia/fisiopatologia , Hipertensão/diagnóstico , Hipertensão/fisiopatologia , Cazaquistão/epidemiologia , Modelos Logísticos , Masculino , Testes de Estado Mental e Demência , Síndrome Metabólica/diagnóstico , Síndrome Metabólica/fisiopatologia , Pessoa de Meia-Idade , Fatores de RiscoRESUMO
The urgency of the problem of metabolic syndrome (MS) is due to the high prevalence and risk of developing cardiovascular complications. Purpose of the study - to investigate the degree of adherence to the Mediterranean diet of the studied sample using the MedDietScore (MDS) questionnaire and to assess the association of score of MDS with the components of metabolic syndrome. A cross-sectional study was conducted, during which a clinical, laboratory examination and questioning of 839 patients was carried out. For assessment of the relationship between the MS, its components and the average MDS score multivariate logistic regression analysis was used. The average score of MDS in the studied population was 20.91 (Me=21.00). The mean MDS score was statistically significantly lower in patients with MS components, compared with patients who did not have these components. The inverse association between adherence to the Mediterranean diet and the components of the MS was revealed.