Detalhe da pesquisa
1.
Structural basis for thioredoxin-mediated suppression of NLRP1 inflammasome.
Nature
; 622(7981): 188-194, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37704723
2.
Structure of the bile acid transporter and HBV receptor NTCP.
Nature
; 606(7916): 1021-1026, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35580629
3.
Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation.
Immunity
; 48(4): 649-658.e4, 2018 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29625894
4.
Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA.
Immunity
; 45(4): 737-748, 2016 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27742543
5.
Structural basis for the oligomerization-mediated regulation of NLRP3 inflammasome activation.
Proc Natl Acad Sci U S A
; 119(11): e2121353119, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35254907
6.
Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity.
EMBO J
; 39(12): e101732, 2020 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32378734
7.
Propofol directly binds to and inhibits TLR7.
FASEB J
; 36(8): e22481, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35899460
8.
Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization.
Nature
; 534(7608): 566-9, 2016 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27309808
9.
The effect of anesthetics on toll like receptor 9.
FASEB J
; 34(11): 14645-14654, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32901993
10.
Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9.
Nature
; 520(7549): 702-5, 2015 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25686612
11.
Small-molecule inhibition of TLR8 through stabilization of its resting state.
Nat Chem Biol
; 14(1): 58-64, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29155428
12.
Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system.
FASEB J
; 33(12): 14528-14541, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31675483
13.
Mechanisms controlling nucleic acid-sensing Toll-like receptors.
Int Immunol
; 30(2): 43-51, 2018 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29452403
14.
Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8.
Proc Natl Acad Sci U S A
; 113(11): 3012-7, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26929371
15.
The crystal structure of the AhRR-ARNT heterodimer reveals the structural basis of the repression of AhR-mediated transcription.
J Biol Chem
; 292(43): 17609-17616, 2017 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28904176
16.
Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex.
J Biol Chem
; 292(37): 15378-15394, 2017 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28754693
17.
Guanosine and its modified derivatives are endogenous ligands for TLR7.
Int Immunol
; 28(5): 211-22, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26489884
18.
Conservation and Divergence of Ligand Recognition and Signal Transduction Mechanisms in Toll-Like Receptors.
Chem Pharm Bull (Tokyo)
; 65(8): 697-705, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28768923
19.
TLR4-MD-2 complex is negatively regulated by an endogenous ligand, globotetraosylceramide.
Proc Natl Acad Sci U S A
; 110(12): 4714-9, 2013 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23471986
20.
Structural basis of pharmacological chaperoning for human ß-galactosidase.
J Biol Chem
; 289(21): 14560-8, 2014 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24737316