Detalhe da pesquisa
1.
ß-II tubulin isotype directs stiffness and differentiation of neuroblastoma SH-SY5Y cells.
Mol Cell Biochem
; 478(9): 1961-1971, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-36585545
2.
Development of QTMP: A promising anticancer agent through NP-Privileged Motif-Driven structural modulation.
Bioorg Med Chem
; 95: 117489, 2023 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37816266
3.
Vitamin K3 inhibits FtsZ assembly, disrupts the Z-ring in Streptococcus pneumoniae and displays anti-pneumococcal activity.
Biochem J
; 479(14): 1543-1558, 2022 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35789252
4.
Microtubule-targeting agents impair kinesin-2-dependent nuclear transport of ß-catenin: Evidence of inhibition of Wnt/ß-catenin signaling as an important antitumor mechanism of microtubule-targeting agents.
FASEB J
; 35(4): e21539, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33742719
5.
Computational study of interactions of anti-cancer drug eribulin with human tubulin isotypes.
Phys Chem Chem Phys
; 24(27): 16694-16700, 2022 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35766982
6.
Hyperthermia induced disruption of mechanical balance leads to G1 arrest and senescence in cells.
Biochem J
; 478(1): 179-196, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33346336
7.
Combinatorial cetuximab targeted polymeric nanocomplexes reduce PRC1 level and abrogate growth of metastatic hepatocellular carcinoma in vivo with efficient radionuclide uptake.
Nanomedicine
; 41: 102529, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35104671
8.
Discovery of 2',6-Bis(4-hydroxybenzyl)-2-acetylcyclohexanone, a Novel FtsZ Inhibitor.
Molecules
; 27(20)2022 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36296585
9.
Design, synthesis, and biological evaluation of benzo[d]imidazole-2-carboxamides as new anti-TB agents.
Bioorg Chem
; 107: 104538, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33349456
10.
Tubulin-Binding 3,5-Bis(styryl)pyrazoles as Lead Compounds for the Treatment of Castration-Resistant Prostate Cancer.
Mol Pharmacol
; 97(6): 409-422, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32241960
11.
Mechanistic insight into the effect of BT-benzo-29 on the Z-ring in Bacillus subtilis.
IUBMB Life
; 72(5): 978-990, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31984664
12.
Inhibition of polo-like kinase 1 suppresses microtubule dynamics in MCF-7 cells.
Mol Cell Biochem
; 465(1-2): 27-36, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31782084
13.
Tubulin heterogeneity regulates functions and dynamics of microtubules and plays a role in the development of drug resistance in cancer.
Biochem J
; 476(9): 1359-1376, 2019 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085712
14.
An acetylation mimicking mutation, K274Q, in tau imparts neurotoxicity by enhancing tau aggregation and inhibiting tubulin polymerization.
Biochem J
; 476(10): 1401-1417, 2019 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31036717
15.
The C-terminal tails of heterotrimeric kinesin-2 motor subunits directly bind to α-tubulin1: Possible implications for cilia-specific tubulin entry.
Traffic
; 18(2): 123-133, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27976831
16.
Mutation of G51 in SepF impairs FtsZ assembly promoting ability of SepF and retards the division of Mycobacterium smegmatis cells.
Biochem J
; 475(15): 2473-2489, 2018 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30006469
17.
Regulation of microtubule stability by centrosomal proteins.
IUBMB Life
; 70(7): 602-611, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29734495
18.
A centrosomal protein FOR20 regulates microtubule assembly dynamics and plays a role in cell migration.
Biochem J
; 474(16): 2841-2859, 2017 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28694353
19.
A Carbocyclic Curcumin Inhibits Proliferation of Gram-Positive Bacteria by Targeting FtsZ.
Biochemistry
; 56(3): 514-524, 2017 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28002947
20.
Mutation of Arg191 in FtsZ Impairs Cytokinetic Abscission of Bacillus subtilis Cells.
Biochemistry
; 55(40): 5754-5763, 2016 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27629358