Detalhe da pesquisa
1.
KRas localizes to the plasma membrane by spatial cycles of solubilization, trapping and vesicular transport.
Cell
; 157(2): 459-471, 2014 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24725411
2.
The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer.
J Biol Chem
; 297(5): 101335, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34688654
3.
Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling.
Nature
; 497(7451): 638-42, 2013 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23698361
4.
Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition.
bioRxiv
; 2024 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38464125
5.
Concurrent Inhibition of IGF1R and ERK Increases Pancreatic Cancer Sensitivity to Autophagy Inhibitors.
Cancer Res
; 82(4): 586-598, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34921013
6.
CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment.
Cell Rep
; 37(9): 110060, 2021 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34852220
7.
Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Nat Med
; 26(6): 982, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32483362
8.
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Nat Med
; 25(4): 628-640, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30833752
9.
Identification of pyrazolopyridazinones as PDEδ inhibitors.
Nat Commun
; 7: 11360, 2016 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27094677
10.
Precise measurement of protein interacting fractions with fluorescence lifetime imaging microscopy.
Mol Biosyst
; 7(2): 322-36, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21221430