Detalhe da pesquisa
1.
Lessons Learned from Approval of Aducanumab for Alzheimer's Disease.
Annu Rev Med
; 75: 99-111, 2024 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38285515
2.
The Cerebellar Cognitive Affective/Schmahmann Syndrome Scale in Spinocerebellar Ataxias.
Cerebellum
; 2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38165578
3.
Blood-based biomarkers for Alzheimer's disease and cognitive function from mid- to late life.
Alzheimers Dement
; 20(3): 1807-1814, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38126555
4.
Patient- and proxy-reported quality of life in advanced dementia with Lewy bodies.
Alzheimers Dement
; 20(4): 2719-2730, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38400528
5.
Impaired Oligodendrocyte Maturation Is an Early Feature in SCA3 Disease Pathogenesis.
J Neurosci
; 42(8): 1604-1617, 2022 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35042771
6.
Disrupting the Balance of Protein Quality Control Protein UBQLN2 Accelerates Tau Proteinopathy.
J Neurosci
; 42(9): 1845-1863, 2022 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35082119
7.
GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin.
J Biol Chem
; 298(8): 102219, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35780830
8.
The S-Factor, a New Measure of Disease Severity in Spinocerebellar Ataxia: Findings and Implications.
Cerebellum
; 22(5): 790-809, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35962273
9.
Mild Cognitive Impairment Subtype Performance in Comparison to Healthy Older Controls on the NIH Toolbox and Cogstate.
Alzheimer Dis Assoc Disord
; 37(4): 328-334, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37862614
10.
Research Priorities of Individuals and Caregivers With Lewy Body Dementia: A Web-based Survey.
Alzheimer Dis Assoc Disord
; 37(1): 50-58, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36821177
11.
Wild-type and pathogenic forms of ubiquilin 2 differentially modulate components of the autophagy-lysosome pathways.
J Pharmacol Sci
; 152(3): 182-192, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37257946
12.
RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control.
Cell Mol Life Sci
; 79(3): 176, 2022 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35247097
13.
Rational affinity maturation of anti-amyloid antibodies with high conformational and sequence specificity.
J Biol Chem
; 296: 100508, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33675750
14.
Ubiquilin-2 differentially regulates polyglutamine disease proteins.
Hum Mol Genet
; 29(15): 2596-2610, 2020 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32681165
15.
Polyglutamine spinocerebellar ataxias - from genes to potential treatments.
Nat Rev Neurosci
; 18(10): 613-626, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28855740
16.
Antisense Oligonucleotide Therapy Targeted Against ATXN3 Improves Potassium Channel-Mediated Purkinje Neuron Dysfunction in Spinocerebellar Ataxia Type 3.
Cerebellum
; 20(1): 41-53, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32789747
17.
Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly.
Proc Natl Acad Sci U S A
; 115(44): E10495-E10504, 2018 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333186
18.
Nature-inspired design and evolution of anti-amyloid antibodies.
J Biol Chem
; 294(21): 8438-8451, 2019 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30918024
19.
Pathogenesis of SCA3 and implications for other polyglutamine diseases.
Neurobiol Dis
; 134: 104635, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31669734
20.
Druggable genome screen identifies new regulators of the abundance and toxicity of ATXN3, the Spinocerebellar Ataxia type 3 disease protein.
Neurobiol Dis
; 137: 104697, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31783119