Detalhe da pesquisa
1.
Nutrient-regulated control of lysosome function by signaling lipid conversion.
Cell
; 186(24): 5328-5346.e26, 2023 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37883971
2.
The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems.
PLoS Biol
; 21(4): e3002044, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37068088
3.
Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy.
EMBO J
; 38(1)2019 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30420558
4.
ZRF1 is a novel S6 kinase substrate that drives the senescence programme.
EMBO J
; 36(6): 736-750, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28242756
5.
mTORC1-mediated translational elongation limits intestinal tumour initiation and growth.
Nature
; 517(7535): 497-500, 2015 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25383520
6.
Selective Tuberous Sclerosis Complex 1 Gene Deletion in Smooth Muscle Activates Mammalian Target of Rapamycin Signaling and Induces Pulmonary Hypertension.
Am J Respir Cell Mol Biol
; 55(3): 352-67, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26991739
7.
Depdc5 knockout rat: A novel model of mTORopathy.
Neurobiol Dis
; 89: 180-9, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26873552
8.
Combination of lipid metabolism alterations and their sensitivity to inflammatory cytokines in human lipin-1-deficient myoblasts.
Biochim Biophys Acta
; 1832(12): 2103-14, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23928362
9.
A homoeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism.
Nat Metab
; 6(2): 323-342, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38409325
10.
Role of PI3K, mTOR and Akt2 signalling in hepatic tumorigenesis via the control of PKM2 expression.
Biochem Soc Trans
; 41(4): 917-22, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863156
11.
Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control.
Nat Cell Biol
; 7(3): 286-94, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15723049
12.
S6 kinase 1 at the central node of cell size and ageing.
Front Cell Dev Biol
; 10: 949196, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36036012
13.
PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruption.
Sci Adv
; 8(49): eade7823, 2022 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36490341
14.
Constitutively active Akt1 expression in mouse pancreas requires S6 kinase 1 for insulinoma formation.
J Clin Invest
; 118(11): 3629-38, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18846252
15.
Regulation of the SREBP transcription factors by mTORC1.
Biochem Soc Trans
; 39(2): 495-9, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21428927
16.
Coordinated maintenance of muscle cell size control by AMP-activated protein kinase.
FASEB J
; 24(9): 3555-61, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20460585
17.
Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling.
Nat Commun
; 12(1): 3660, 2021 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34135321
18.
Important role for AMPKalpha1 in limiting skeletal muscle cell hypertrophy.
FASEB J
; 23(7): 2264-73, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19237506
19.
mTOR and S6K1 drive polycystic kidney by the control of Afadin-dependent oriented cell division.
Nat Commun
; 11(1): 3200, 2020 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32581239
20.
A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas.
Dev Cell
; 51(1): 113-128.e9, 2019 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31447265