Detalhe da pesquisa
1.
Structural basis of efficacy-driven ligand selectivity at GPCRs.
Nat Chem Biol
; 19(7): 805-814, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36782010
2.
A novel iPSC model reveals selective vulnerability of neurons in multiple sulfatase deficiency.
Mol Genet Metab
; 141(2): 108116, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38161139
3.
Biochemical signatures of disease severity in multiple sulfatase deficiency.
J Inherit Metab Dis
; 47(2): 374-386, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37870986
4.
Beta-lactam allergy risk stratification in a maternity population in Australia: Scope for allergy de-labelling.
Aust N Z J Obstet Gynaecol
; 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38721775
5.
Role of Conserved Tyrosine Lid Residues in the Activation of the M2 Muscarinic Acetylcholine Receptor.
Mol Pharmacol
; 104(3): 92-104, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37348914
6.
Positive allosteric modulation of endogenous delta opioid receptor signaling in the enteric nervous system is a potential treatment for gastrointestinal motility disorders.
Am J Physiol Gastrointest Liver Physiol
; 322(1): G66-G78, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34755545
7.
Nesfatin-1 stimulates the hypothalamus-pituitary-interrenal axis hormones in goldfish.
Am J Physiol Regul Integr Comp Physiol
; 321(4): R603-R613, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34405712
8.
Three-dimensional quantitative MRI of aerosolized gadolinium-based nanoparticles and contrast agents in isolated ventilated porcine lungs.
Magn Reson Med
; 83(5): 1774-1782, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31654446
9.
Author Correction: Structural basis of efficacy-driven ligand selectivity at GPCRs.
Nat Chem Biol
; 19(4): 529, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36879062
10.
Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a.
Proc Natl Acad Sci U S A
; 114(14): 3750-3755, 2017 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28320941
11.
Binding to and Inhibition of Insulin-Regulated Aminopeptidase by Macrocyclic Disulfides Enhances Spine Density.
Mol Pharmacol
; 89(4): 413-24, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26769413
12.
Chronic GLP1 therapy reduces postprandial IL6 in obese humans with prediabetes.
Cardiovasc Endocrinol Metab
; 13(1): e0298, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38187405
13.
Effective Gene Therapy for Metachromatic Leukodystrophy Achieved with Minimal Lentiviral Genomic Integrations.
bioRxiv
; 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38559013
14.
Conversion of Phenolic Acids in Canola Fermentation: Impact on Antimicrobial Activity against Salmonella enterica and Campylobacter jejuni.
J Agric Food Chem
; 71(4): 2059-2069, 2023 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36669157
15.
Inhibition of insulin-regulated aminopeptidase confers neuroprotection in a conscious model of ischemic stroke.
Sci Rep
; 13(1): 19722, 2023 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37957163
16.
Cohort profile: The SmartSleep Study, Denmark, combining evidence from survey, clinical and tracking data.
BMJ Open
; 13(10): e063588, 2023 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37793923
17.
Structure-activity relationship of pyrazol-4-yl-pyridine derivatives and identification of a radiofluorinated probe for imaging the muscarinic acetylcholine receptor M4.
Acta Pharm Sin B
; 13(1): 213-226, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36815036
18.
Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR.
Nat Commun
; 14(1): 5440, 2023 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37673901
19.
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics.
Elife
; 122023 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37248726
20.
The Design, Synthesis, and Evaluation of Novel 9-Arylxanthenedione-Based Allosteric Modulators for the δ-Opioid Receptor.
J Med Chem
; 65(18): 12367-12385, 2022 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36099150