Detalhe da pesquisa
1.
Direct-to-biology platform: From synthesis to biological evaluation of SHP2 allosteric inhibitors.
Bioorg Med Chem Lett
; 100: 129626, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38266789
2.
SAR evolution towards potent C-terminal carboxamide peptide inhibitors of Zika virus NS2B-NS3 protease.
Bioorg Med Chem
; 57: 116631, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35123179
3.
Discovery of 4-((1-(1H-imidazol-2-yl)alkoxy)methyl)pyridines as a new class of Trypanosoma cruzi growth inhibitors.
Bioorg Med Chem Lett
; 30(8): 127052, 2020 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32113841
4.
Optimization of 2-(1H-imidazo-2-yl)piperazines series of Trypanosoma brucei growth inhibitors as potential treatment for the second stage of HAT.
Bioorg Med Chem Lett
; 30(12): 127207, 2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32354566
5.
Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitro.
Bioorg Med Chem Lett
; 28(23-24): 3689-3692, 2018 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30482621
6.
Discovery of a Novel Series of Imidazopyrazine Derivatives as Potent SHP2 Allosteric Inhibitors.
ACS Med Chem Lett
; 14(2): 156-162, 2023 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36793438
7.
Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides.
ACS Med Chem Lett
; 10(4): 481-486, 2019 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30996783
8.
Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs.
ACS Med Chem Lett
; 7(5): 454-9, 2016 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27190592
9.
Optimization of thienopyrrole-based finger-loop inhibitors of the hepatitis C virus NS5B polymerase.
ChemMedChem
; 4(10): 1695-713, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19672916
10.
Identification of thieno[3,2-b]pyrroles as allosteric inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 16(15): 4026-30, 2006 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16714108
11.
Capped dipeptide alpha-ketoacid inhibitors of the HCV NS3 protease.
Bioorg Med Chem Lett
; 12(22): 3325-8, 2002 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-12392743
12.
Active site inhibitors of HCV NS5B polymerase. The development and pharmacophore of 2-thienyl-5,6-dihydroxypyrimidine-4-carboxylic acid.
Bioorg Med Chem Lett
; 14(20): 5085-8, 2004 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-15380204