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1.
J Pharm Bioallied Sci ; 15(Suppl 2): S916-S919, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37694080

RESUMO

Need for the Study: The mental branch of the trigeminal nerve, which supplies sensation to the lower lip, originates in the mandibular canal, making it an essential anatomical structure for dentists and oral surgeons to access. It is not well known that there is a spectrum of normal that includes variants in which there may be more than one nerve entry site, which means that if the mental foramen is not protected, normal feeling in the lower lip may be lost permanently. The diagnostic value of global radiographic landmarks like the mandibular trench and the dental foramen in identifying skeletal problems has been investigated. Materials and Methods: Four hundred patients over 40 who fit the inclusion/exclusion criteria were chosen. Patients were recruited from Vananchal Dental College and Hospital, Garhwa's Out Patient section for Oral Medicine, Diagnosis, and Radiology. The following patients with their consent are subjected for digital orthopantomography (Cephalometric Device for Rotograph EVOD Ref 930790001, SN 14112930, Villa Sistem Medical) and the captured images are then interpreted for the variations in mandibular canal. Result: The results of our study are as follows: In this study, the mean age of the subjects was 47.27 years, with a range of 40-75 yearsMajority of cases were females (53.75%) and 46.25% were males.The top of the residual ridge, located between the mental foramen and the mandibular canal, is clearly visible to all observers (grade I).Only 1.75% of the people surveyed had a bifid canal, despite the fact that the majority of the people surveyed had a single mandibular canal on both sides (98.25%).Right side mean was 18,682.017, whereas left side mean was 16,331.851; nevertheless, this difference was not statistically significant (P = 0.0860 NS). Conclusion: The dental foramen was located close to where the mandible and the area housing the next premolar met. These findings may be utilized to improve the safety of peri-apical surgical procedures. Therefore, it is therapeutically relevant to get insight into the structural alterations of the mental foramen and locate its location in preoperative radiological scans.

2.
Cureus ; 15(9): e46195, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37905250

RESUMO

Background Socio-cultural considerations (such as drug availability) and psychological traits play a significant role in predicting whether a person will use drugs in the future and dependency on the drugs. Second-, third-, and fourth-hand smoking and E-cigarettes are influencing factors for the use of tobacco in college students. This study conducted research to ascertain whether there is a potential relationship between tobacco consumption and various factors, including internal and external control sites and demographics. Materials and methods Participants in the study were found by walk-up distribution at multiple campus-wide smoking places, department announcements, and on-campus advertisements. Social media and participant references were also used in this study as recruitment tools. In addition, the locus of control questionnaire also identifies if the participating individual had extrinsic or intrinsic reinforcing routines. The classification of the participating individuals into respective internal and external locus of control was in accordance with their response survey after which a statistical analysis was done. Results This study found an association between smoking on campus and reported attempts to quit. Additionally, there is a strong association (r(85) = 0.31, p < 0.01) between reported tobacco use status and cigarette use on campus. Participants' gender and smoking status also had r(85) = 0.39, p-value < 0.01 correlation. The bulk of respondents indicated that they were seniors and off-campus living concluding for 36% (n = 34) and 60% (n = 51) of the total. Twenty-seven percent (n = 24) of the respondents were first-year college students and the rest 33% (n = 29) said their parents had no college education at all or incomplete college education. Conclusion Whenever there is a strong perception of organizational support for anti-tobacco policies, and improving compliance, there is a drastic increase in cigarette cessation and a drop in tobacco usage among those who still smoke. Perceived organizational support is strongly and positively connected with cessation among the organization's members.

3.
Am J Cardiol ; 101(6): 820-4, 2008 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-18328847

RESUMO

The purpose of this study was to evaluate the accuracy of detector computed tomographic angiographic qualitative and quantitative analyses for the detection of in-stent restenosis (ISR) Previous studies have used qualitative analyses exclusively and have excluded "unevaluable" stents. Multidetector computed tomographic angiography (MDCT) was performed before quantitative coronary angiography in 67 patients with 132 stents that were evaluated by 2 techniques: (1) qualitative, on the basis of degree of visual hypodensity, and (2) quantitative, comparing in-stent with prestent Hounsfield units. All stents were evaluated, irrespective of image quality. The incidence of ISR was 12.5%. The sensitivity (94%), specificity (74%), and positive predictive value (39%) of the qualitative evaluation were superior to the quantitative technique (82%, 54%, and 21%, respectively); negative predictive values were similar (99% vs 95%). Accuracies were equal in stents located in proximal and distal vessels. In conclusion, ISR can be evaluated qualitatively by 64-slice MDCT with excellent sensitivity and negative predictive accuracy without exclusion of unevaluable stents and with reasonable specificity but low positive predictive value. Quantitative analysis was less accurate.


Assuntos
Angiografia Coronária/métodos , Reestenose Coronária/diagnóstico por imagem , Stents , Tomografia Computadorizada por Raios X/métodos , Diagnóstico Diferencial , Erros de Diagnóstico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Falha de Prótese , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
4.
N Engl J Med ; 346(11): 793-801, 2002 Mar 14.
Artigo em Inglês | MEDLINE | ID: mdl-11893790

RESUMO

BACKGROUND: Exercise capacity is known to be an important prognostic factor in patients with cardiovascular disease, but it is uncertain whether it predicts mortality equally well among healthy persons. There is also uncertainty regarding the predictive power of exercise capacity relative to other clinical and exercise-test variables. METHODS: We studied a total of 6213 consecutive men referred for treadmill exercise testing for clinical reasons during a mean (+/-SD) of 6.2+/-3.7 years of follow-up. Subjects were classified into two groups: 3679 had an abnormal exercise-test result or a history of cardiovascular disease, or both, and 2534 had a normal exercise-test result and no history of cardiovascular disease. Overall mortality was the end point. RESULTS: There were a total of 1256 deaths during the follow-up period, resulting in an average annual mortality of 2.6 percent. Men who died were older than those who survived and had a lower maximal heart rate, lower maximal systolic and diastolic blood pressure, and lower exercise capacity. After adjustment for age, the peak exercise capacity measured in metabolic equivalents (MET) was the strongest predictor of the risk of death among both normal subjects and those with cardiovascular disease. Absolute peak exercise capacity was a stronger predictor of the risk of death than the percentage of the age-predicted value achieved, and there was no interaction between the use or nonuse of beta-blockade and the predictive power of exercise capacity. Each 1-MET increase in exercise capacity conferred a 12 percent improvement in survival. CONCLUSIONS: Exercise capacity is a more powerful predictor of mortality among men than other established risk factors for cardiovascular disease.


Assuntos
Tolerância ao Exercício , Mortalidade , Antagonistas Adrenérgicos beta/uso terapêutico , Idoso , Pressão Sanguínea , Índice de Massa Corporal , Doenças Cardiovasculares/mortalidade , Doenças Cardiovasculares/fisiopatologia , Teste de Esforço , Tolerância ao Exercício/fisiologia , Seguimentos , Frequência Cardíaca , Humanos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Prognóstico , Modelos de Riscos Proporcionais , Curva ROC , Risco , Fatores de Risco , Análise de Sobrevida
5.
Food Chem ; 213: 768-774, 2016 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-27451246

RESUMO

In this study, bread was baked with and without the addition of α-amylase. Starch was extracted from the baked bread and its molecular properties were characterized using (1)H NMR and asymmetric flow field-flow fractionation (AF4) connected to multi-angle light scattering (MALS) and other detectors. The approach allows determination of molar mass, root- mean-square radius and apparent density as well as the average degree of branching of amylopectin. The results show that starch size and structure is affected as a result of the baking process. The effect is larger when α-amylase is added. The changes include both a decrease molar mass and size as well as an increase in apparent density. Moreover, an increase in average degree of branching and the number of reducing ends H-1(ß-r) and H-1(α-r) can be observed.


Assuntos
Culinária , Amido/química , Triticum/química , alfa-Amilases/química , Amilopectina/química , Pão/análise , Fenômenos Químicos , Fracionamento por Campo e Fluxo , Espectroscopia de Ressonância Magnética , Peso Molecular
6.
Arch Intern Med ; 163(18): 2204-10, 2003 Oct 13.
Artigo em Inglês | MEDLINE | ID: mdl-14557218

RESUMO

BACKGROUND: Ethnic differences in the relationship between access to health care and survival are difficult to define because of many confounding factors, such as socioeconomic status and baseline differences in health. Because the Veterans Affairs health care system offers health care largely without financial considerations, it provides an ideal setting in which to identify and understand ethnic differences in health outcomes. Previous studies in this area have lacked clinical and cardiovascular data with which to adjust for baseline differences in patients' health. METHODS: Data were collected from consecutive men referred for resting electrocardiography (ECG) (n = 41 087) or exercise testing (n = 6213) during 12 years. We compared ethnic differences in survival between whites, blacks, and Hispanics after considering baseline differences in age and hospitalization status. We also adjusted for electrocardiogram abnormalities and cardiac risk factors, exercise test results, and cardiovascular comorbidities. RESULTS: White patients tended to be older and had more baseline comorbidities and cardiovascular interventions when they presented for testing. White patients had increased mortality rates compared with blacks and Hispanics. In the ECG population, after adjusting for demographics and baseline electrocardiogram abnormalities, Hispanics had improved survival compared with whites and blacks. In the exercise test population, after adjusting for the same factors, as well as adjusting for the presence of cardiovascular comorbidities, cardiac risk factors, and exercise test findings, Hispanics also exhibited improved survival compared with the other 2 ethnicities. There were no differences in mortality rates between whites and blacks. CONCLUSION: Our findings demonstrate that the health care provided to veterans referred for routine ECG or exercise testing is not associated with poorer survival in ethnic minorities.


Assuntos
Doenças Cardiovasculares/etnologia , Doenças Cardiovasculares/mortalidade , Etnicidade , Veteranos , Idoso , California/epidemiologia , Teste de Esforço , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de Risco , Análise de Sobrevida
7.
Am J Med ; 112(6): 453-9, 2002 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-11959055

RESUMO

PURPOSE: Our purposes were to compare the responses to exercise testing in elderly (> or =65 years of age) and younger men, and to investigate whether exercise testing has similar prognostic value in the two age groups. METHODS: We included all elderly (n = 1185) and younger (n = 2789) male veterans without established coronary heart disease who underwent routine clinical exercise testing between 1987 and 2000 at two academically affiliated Veteran's Affairs medical center laboratories. Measurements included a standardized medical history, exercise testing, and all-cause mortality. RESULTS: Compared with younger patients, elderly patients achieved a lower workload (a mean [+/- SD] of 7 +/- 3 vs. 10 +/- 4 metabolic equivalents [METs], P <0.001) and were more likely to have abnormal ST depression (27% [n = 324] vs. 16% [n = 436], P <0.001). During the mean follow-up of 6 years, annual mortality was twice as high among elderly patients as among younger patients (4% vs. 2%, P <0.001). The only exercise test variable that was associated significantly with time to death in both age groups was maximal METs achieved: each 1 MET increase in exercise capacity was associated with an 11% reduction in annual mortality. Exercise-induced ST depression was more common in those who subsequently died, but was not an independent predictor of mortality. CONCLUSION: In elderly men, exercise testing provided prognostic information incremental to clinical data. Achieved workload (in METs) was the major exercise testing variable associated with all-cause mortality. Its prognostic importance was the same in elderly as in younger men.


Assuntos
Doenças Cardiovasculares/mortalidade , Doenças Cardiovasculares/fisiopatologia , Teste de Esforço , Sistema de Condução Cardíaco/fisiologia , Fatores Etários , Idoso , Doenças Cardiovasculares/tratamento farmacológico , Eletrocardiografia , Seguimentos , Sistema de Condução Cardíaco/fisiopatologia , Hospitais de Veteranos , Humanos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Prognóstico , Fatores de Risco , Análise de Sobrevida
8.
Clin Gastroenterol Hepatol ; 2(6): 459-62, 2004 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-15181612

RESUMO

BACKGROUND & AIMS: The goal of this study was to uncover possible racial-ethnic differences in hepatitis C presentation in an urban hepatitis clinic. METHODS: We surveyed the clinic summary cards of patients with antibodies to hepatitis C virus (HCV) seen from 1993 to 2000 for demographic and laboratory data. RESULTS: A total of 1271 HCV patients were categorized into 4 major racial-ethnic groups consisting of 95 Asian, 232 African American, 323 Caucasian, and 621 Latino patients. The latter showed significantly higher serum alanine transaminase (ALT), aspartate transaminase, and bilirubin levels (P < 0.0001) and lower serum albumin levels (P < 0.01) compared with all other racial-ethnic groups. Latinos had the lowest rate of hepatitis B coinfection (2.4%) and were significantly less likely to have normal serum ALT levels (P = 0.0002) compared with other groups. Asian patients were 10 years older than other racial-ethnic groups and were significantly more likely to be coinfected with hepatitis B virus (HBV) (P = 0.004). Asian patients also had an equal distribution of infected men and women whereas all other groups showed a male predominance. Injection drug use was a negligible cause of hepatitis C in Asian patients, but a prevalent exposure in Caucasian patients of both sexes and in African American and Latino men was seen. Transfusion was more prevalent in Asian and Latino patients. CONCLUSIONS: Hepatitis C risk factors, sex distribution, and coinfection with hepatitis B vary by race-ethnicity. Latino patients showed statistically significant biochemical differences in ALT, aspartate transaminase, bilirubin, and albumin levels compared with all other racial-ethnic groups. Further studies are required to determine the possible causes for these biochemical differences.


Assuntos
Asiático , Negro ou Afro-Americano , Hepatite C/etnologia , Hepatite C/metabolismo , Hispânico ou Latino , População Branca , Adulto , Alanina Transaminase/sangue , Instituições de Assistência Ambulatorial , Aspartato Aminotransferases/sangue , Bilirrubina/sangue , Feminino , Humanos , Testes de Função Hepática , Los Angeles/epidemiologia , Masculino , Pessoa de Meia-Idade , Contagem de Plaquetas , Protrombina/metabolismo , Estudos Retrospectivos , Albumina Sérica/metabolismo , Saúde da População Urbana
9.
Am J Phys Med Rehabil ; 81(8): 601-8, 2002 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-12172070

RESUMO

OBJECTIVE: To demonstrate the prevalence and prognostic value of electrocardiographic abnormalities in patients with chronic spinal cord injury. METHODS: All electrocardiographs obtained in the Palo Alto Veterans Affairs Medical Center since 1987 have been digitally recorded and stored in a computerized database. For this study, only the first electrocardiograph was considered for analysis. The subjects were divided according to age and level of spinal cord injury. The Social Security Death Index was used to ascertain vital status as of December 1999. RESULTS: Annual mortality was similar in those with chronic spinal cord injury and the able-bodied. However, individuals with a higher level of injury had a significantly higher death rate than those with a lower level of injury. The prognostic characteristics of electrocardiographic abnormalities were similar in both the able-bodied and those with spinal cord injury. CONCLUSION: In general, electrocardiographic abnormalities had the same prevalence in the spinal cord injury subjects as in the able-bodied ones. The prognostic value of electrocardiographic abnormalities in subjects with spinal cord injury is similar to that observed in able-bodied subjects.


Assuntos
Arritmias Cardíacas/complicações , Arritmias Cardíacas/epidemiologia , Eletrocardiografia , Traumatismos da Medula Espinal/complicações , Adulto , Fatores Etários , Idoso , Arritmias Cardíacas/diagnóstico , Doença Crônica , Humanos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Prevalência , Prognóstico , Estudos Retrospectivos , Traumatismos da Medula Espinal/epidemiologia , Análise de Sobrevida
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