Detalhe da pesquisa
1.
Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution.
Cell
; 165(1): 234-246, 2016 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26924578
2.
Deciphering the Mechanistic Basis for Perfluoroalkyl-Protein Interactions.
Chembiochem
; 24(13): e202300159, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36943393
3.
The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning.
Proc Natl Acad Sci U S A
; 117(8): 4053-4060, 2020 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32041867
4.
A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth.
Genes Dev
; 29(5): 483-8, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25737277
5.
Materials-driven approaches to understand extrinsic drug resistance in cancer.
Soft Matter
; 18(18): 3465-3472, 2022 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35445686
6.
Optimal SARS-CoV-2 vaccine allocation using real-time attack-rate estimates in Rhode Island and Massachusetts.
BMC Med
; 19(1): 162, 2021 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34253200
7.
Synthesis, structure and anticancer properties of new biotin- and morpholine-functionalized ruthenium and osmium half-sandwich complexes.
J Biol Inorg Chem
; 26(5): 535-549, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34173882
8.
Evolution of the nonsense-mediated decay pathway is associated with decreased cytolytic immune infiltration.
PLoS Comput Biol
; 15(10): e1007467, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31658270
9.
Inherited Disease Genetics Improves the Identification of Cancer-Associated Genes.
PLoS Genet
; 12(6): e1006081, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27304678
10.
ARTIST: high-resolution genome-wide assessment of fitness using transposon-insertion sequencing.
PLoS Genet
; 10(11): e1004782, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25375795
11.
Defining principles of combination drug mechanisms of action.
Proc Natl Acad Sci U S A
; 110(2): E170-9, 2013 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23251029
12.
High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model-based analyses of transposon-insertion sequencing data.
Nucleic Acids Res
; 41(19): 9033-48, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23901011
13.
Disruption of Mycobacterium avium subsp. paratuberculosis-specific genes impairs in vivo fitness.
BMC Genomics
; 15: 415, 2014 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-24885784
14.
A mammalian functional-genetic approach to characterizing cancer therapeutics.
Nat Chem Biol
; 7(2): 92-100, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21186347
15.
Understanding resistance to combination chemotherapy.
Drug Resist Updat
; 15(5-6): 249-57, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23164555
16.
Excessive concentrations of kinase inhibitors in translational studies impede effective drug repurposing.
Cell Rep Med
; 4(10): 101227, 2023 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37852183
17.
Functional genomic analysis of adult and pediatric brain tumor isolates.
bioRxiv
; 2023 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711964
18.
A pan-CRISPR analysis of mammalian cell specificity identifies ultra-compact sgRNA subsets for genome-scale experiments.
Nat Commun
; 13(1): 625, 2022 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35110534
19.
Agent-Based Models Help Interpret Patterns of Clinical Drug Resistance by Contextualizing Competition Between Distinct Drug Failure Modes.
Cell Mol Bioeng
; 15(5): 521-533, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-36444351
20.
Phase II Study of Ponatinib in Advanced Gastrointestinal Stromal Tumors: Efficacy, Safety, and Impact of Liquid Biopsy and Other Biomarkers.
Clin Cancer Res
; 28(7): 1268-1276, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35091442