Detalhe da pesquisa
1.
Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound.
Proc Natl Acad Sci U S A
; 120(28): e2219543120, 2023 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37406092
2.
Nuclear GAPDH in cortical microglia mediates cellular stress-induced cognitive inflexibility.
Mol Psychiatry
; 2024 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38615102
3.
Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone.
Mol Psychiatry
; 29(3): 624-632, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38145984
4.
Neuronal deletion of nSMase2 reduces the production of Aß and directly protects neurons.
Neurobiol Dis
; 177: 105987, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36603748
5.
The Effects of the Dopamine Transporter Ligands JJC8-088 and JJC8-091 on Cocaine versus Food Choice in Rhesus Monkeys.
J Pharmacol Exp Ther
; 384(3): 372-381, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36507847
6.
Cocaine-induced locomotor stimulation involves autophagic degradation of the dopamine transporter.
Mol Psychiatry
; 26(2): 370-382, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33414501
7.
Thionated aminofluorophthalimides reduce classical markers of cellular inflammation in LPS-challenged RAW 264.7 cells.
Bioorg Med Chem Lett
; 76: 128972, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36265914
8.
A role for mast cells in geographic atrophy.
FASEB J
; 34(8): 10117-10131, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32525594
9.
Model studies towards prodrugs of the glutamine antagonist 6-diazo-5-oxo-l-norleucine (DON) containing a diazo precursor.
Bioorg Med Chem Lett
; 50: 128321, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34400301
10.
Looking for Drugs in All the Wrong Places: Use of GCPII Inhibitors Outside the Brain.
Neurochem Res
; 45(6): 1256-1267, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31749072
11.
Allosteric kidney-type glutaminase (GLS) inhibitors with a mercaptoethyl linker.
Bioorg Med Chem
; 28(20): 115698, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33069080
12.
DCC-related developmental effects of abused- versus therapeutic-like amphetamine doses in adolescence.
Addict Biol
; 25(4): e12791, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31192517
13.
Enhanced Oral Bioavailability of 2-(Phosphonomethyl)-pentanedioic Acid (2-PMPA) from its (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl (ODOL)-Based Prodrugs.
Mol Pharm
; 16(10): 4292-4301, 2019 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31503493
14.
Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer.
Proc Natl Acad Sci U S A
; 113(36): E5328-36, 2016 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27559084
15.
Glutamine metabolism via glutaminase 1 in autosomal-dominant polycystic kidney disease.
Nephrol Dial Transplant
; 33(8): 1343-1353, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29420817
16.
Ponesimod, a selective sphingosine 1-phosphate (S1P1) receptor modulator for autoimmune diseases: review of clinical pharmacokinetics and drug disposition.
Xenobiotica
; 48(5): 442-451, 2018 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28489480
17.
Stereoselective and nonstereoselective pharmacokinetics of rabeprazole - an overview.
Xenobiotica
; 48(4): 422-432, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28294690
18.
Chirality and neuropsychiatric drugs: an update on stereoselective disposition and clinical pharmacokinetics of bupropion.
Xenobiotica
; 48(9): 945-957, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28876959
19.
A review of bioanalytical quantitative methods for selected sphingosine 1-phosphate receptor modulators.
Biomed Chromatogr
; 32(1)2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28990207
20.
Enhanced Brain Delivery of 2-(Phosphonomethyl)pentanedioic Acid Following Intranasal Administration of Its γ-Substituted Ester Prodrugs.
Mol Pharm
; 14(10): 3248-3257, 2017 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28763226