Detalhe da pesquisa
1.
PAI-1 Deficiency Drives Pulmonary Vascular Smooth Muscle Remodeling and Pulmonary Hypertension.
Am J Physiol Lung Cell Mol Physiol
; 2024 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38860847
2.
Ex vivo therapeutic screening of metastatic cSCC: A review of methodological considerations for clinical implementation.
Exp Dermatol
; 33(4): e15089, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38659312
3.
EGFR and PI3K Signalling Pathways as Promising Targets on Circulating Tumour Cells from Patients with Metastatic Gastric Adenocarcinoma.
Int J Mol Sci
; 25(10)2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38791602
4.
Comparing Genomic Landscapes of Oral and Cutaneous Squamous Cell Carcinoma of the Head and Neck: Quest for Novel Diagnostic Markers.
Mod Pathol
; 36(8): 100190, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37080394
5.
Demystifying emerging bulk RNA-Seq applications: the application and utility of bioinformatic methodology.
Brief Bioinform
; 22(6)2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34329375
6.
Recent Advances in Targeting the Urokinase Plasminogen Activator with Nanotherapeutics.
Mol Pharm
; 20(6): 2766-2780, 2023 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37119285
7.
Automated Patch Clamp Screening of Amiloride and 5-N,N-Hexamethyleneamiloride Analogs Identifies 6-Iodoamiloride as a Potent Acid-Sensing Ion Channel Inhibitor.
Mol Pharm
; 20(7): 3367-3379, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37260417
8.
Human pregnancy zone protein stabilizes misfolded proteins including preeclampsia- and Alzheimer's-associated amyloid beta peptide.
Proc Natl Acad Sci U S A
; 116(13): 6101-6110, 2019 03 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30850528
9.
Systematic evaluation of structure-property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N,N-hexamethylene)amiloride.
Bioorg Med Chem
; 37: 116116, 2021 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33799173
10.
Screening of 5- and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors.
Int J Mol Sci
; 22(6)2021 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33804289
11.
Roles of the Na+/H+ Exchanger Isoform 1 and Urokinase in Prostate Cancer Cell Migration and Invasion.
Int J Mol Sci
; 22(24)2021 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34948058
12.
Design, synthesis and evaluation of carbamate-linked uridyl-based inhibitors of human ST6Gal I.
Bioorg Med Chem
; 28(14): 115561, 2020 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32616185
13.
Comprehensive Mutational and Phenotypic Characterization of New Metastatic Cutaneous Squamous Cell Carcinoma Cell Lines Reveal Novel Drug Susceptibilities.
Int J Mol Sci
; 21(24)2020 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33333825
14.
Paracrine recruitment and activation of fibroblasts by c-Myc expressing breast epithelial cells through the IGFs/IGF-1R axis.
Int J Cancer
; 145(10): 2827-2839, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31381136
15.
6-Substituted amiloride derivatives as inhibitors of the urokinase-type plasminogen activator for use in metastatic disease.
Bioorg Med Chem Lett
; 29(24): 126753, 2019 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31679971
16.
Amorphous protein aggregates stimulate plasminogen activation, leading to release of cytotoxic fragments that are clients for extracellular chaperones.
J Biol Chem
; 292(35): 14425-14437, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28710283
17.
Analysis of clinically relevant somatic mutations in high-risk head and neck cutaneous squamous cell carcinoma.
Mod Pathol
; 31(2): 275-287, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28984303
18.
Sidedness is prognostic in locoregional colon cancer: an analysis of 9509 Australian patients.
BMC Cancer
; 17(1): 251, 2017 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28390415
19.
Probing the pharmacokinetics of cucurbit[7, 8 and 10]uril: and a dinuclear ruthenium antimicrobial complex encapsulated in cucurbit[10]uril.
Org Biomol Chem
; 15(19): 4172-4179, 2017 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28443914
20.
Synthesis and preliminary evaluation of 5,7-dimethyl-2-aryl-3H-pyrrolizin-3-ones as angiogenesis inhibitors.
Bioorg Med Chem Lett
; 26(7): 1813-6, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26912111