Detalhe da pesquisa
1.
The Peptide Antibiotic Corramycin Adopts a ß-Hairpin-like Structure and Is Inactivated by the Kinase ComG.
J Am Chem Soc
; 146(13): 8981-8990, 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38513269
2.
Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents.
Arch Pharm (Weinheim)
; 357(4): e2300656, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38304944
3.
Correction: Fries et al. Impact of Drug Administration Routes on the In Vivo Efficacy of the Natural Product Sorangicin A Using a Staphylococcus aureus Infection Model in Zebrafish Embryos. Int. J. Mol. Sci. 2023, 24, 12791.
Int J Mol Sci
; 25(4)2024 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38397128
4.
Pineapple Lectin AcmJRL Binds SARS-CoV-2 Spike Protein in a Carbohydrate-Dependent Fashion.
Chembiochem
; 24(3): e202200463, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36420784
5.
Impact of Drug Administration Routes on the In Vivo Efficacy of the Natural Product Sorangicin a Using a Staphylococcus aureus Infection Model in Zebrafish Embryos.
Int J Mol Sci
; 24(16)2023 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37628971
6.
Novel 2,4-disubstituted quinazoline analogs as antibacterial agents with improved cytotoxicity profile: Modification of the benzenoid part.
Bioorg Med Chem Lett
; 59: 128531, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35007723
7.
Novel 2,4-disubstituted quinazoline analogs as antibacterial agents with improved cytotoxicity profile: Optimization of the 2,4-substituents.
Bioorg Chem
; 117: 105422, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34700110
8.
Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners.
Molecules
; 26(16)2021 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34443518
9.
Molecular characterization, toxin detection and resistance testing of human clinical Clostridium difficile isolates from Lebanon.
Int J Med Microbiol
; 308(3): 358-363, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29478838
10.
Metabolism and cytotoxicity studies of the two hallucinogens 1cP-LSD and 4-AcO-DET in human liver and zebrafish larvae models using LC-HRMS/MS and a high-content screening assay.
J Pharm Biomed Anal
; 245: 116187, 2024 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38692215
11.
Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins.
Nat Commun
; 15(1): 791, 2024 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38278788
12.
Molecular Characteristics of Colistin Resistance in Acinetobacter baumannii and the Activity of Antimicrobial Combination Therapy in a Tertiary Care Medical Center in Lebanon.
Microorganisms
; 12(2)2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38399753
13.
Evaluation of extraction methods for untargeted metabolomic studies for future applications in zebrafish larvae infection models.
Sci Rep
; 13(1): 7489, 2023 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37161044
14.
Proteoid biodynamers for safe mRNA transfection via pH-responsive nanorods enabling endosomal escape.
J Control Release
; 353: 915-929, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36521693
15.
Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization.
Eur J Med Chem
; 245(Pt 2): 114916, 2023 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36399878
16.
Zebrafish: An Attractive Model to Study Staphylococcus aureus Infection and Its Use as a Drug Discovery Tool.
Pharmaceuticals (Basel)
; 14(6)2021 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34205723
17.
Natural products and polysorbates: Potential Inhibitors of biofilm formation in Pseudomonas aeruginosa.
J Infect Dev Ctries
; 14(6): 580-588, 2020 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32683348
18.
Incidence, outcome, and risk factors for recurrence of nosocomial Clostridioides difficile infection in adults: A prospective cohort study.
J Infect Public Health
; 13(4): 485-490, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-31838001
19.
Evaluating the Efficacies of Carbapenem/ß-Lactamase Inhibitors Against Carbapenem-Resistant Gram-Negative Bacteria in vitro and in vivo.
Front Microbiol
; 10: 933, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31114565
20.
Assessing the effect of micafungin on Pseudomonas aeruginosa biofilm formation using confocal microscopy and gene expression.
J Infect Dev Ctries
; 12(2.1): 8S, 2018 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31804983