Detalhe da pesquisa
1.
Results from tandem Phase 1 studies evaluating the safety, reactogenicity and immunogenicity of the vaccine candidate antigen Plasmodium falciparum FVO merozoite surface protein-1 (MSP1(42)) administered intramuscularly with adjuvant system AS01.
Malar J
; 12: 29, 2013 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23342996
2.
Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization.
Malar J
; 6: 135, 2007 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17925026
3.
First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers.
Vaccine
; 31(43): 4975-83, 2013 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24029408
4.
Human adenovirus 5-vectored Plasmodium falciparum NMRC-M3V-Ad-PfCA vaccine encoding CSP and AMA1 is safe, well-tolerated and immunogenic but does not protect against controlled human malaria infection.
Hum Vaccin Immunother
; 9(10): 2165-77, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23899517
5.
DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity.
PLoS One
; 8(2): e55571, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23457473
6.
Clinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage Plasmodium falciparum DNA vaccine combined with escalating dose human GM-CSF DNA.
Hum Vaccin Immunother
; 8(11): 1564-84, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23151451
7.
Adenovirus 5-vectored P. falciparum vaccine expressing CSP and AMA1. Part A: safety and immunogenicity in seronegative adults.
PLoS One
; 6(10): e24586, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22003383
8.
Adenovirus-5-vectored P. falciparum vaccine expressing CSP and AMA1. Part B: safety, immunogenicity and protective efficacy of the CSP component.
PLoS One
; 6(10): e25868, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22003411
9.
Sterile protection against Plasmodium knowlesi in rhesus monkeys from a malaria vaccine: comparison of heterologous prime boost strategies.
PLoS One
; 4(8): e6559, 2009 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19668343