Detalhe da pesquisa
1.
Inhibition of the KCa3.1 Channel Alleviates Established Pulmonary Fibrosis in a Large Animal Model.
Am J Respir Cell Mol Biol
; 56(4): 539-550, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28060543
2.
Lipoxin A4 Attenuates Constitutive and TGF-ß1-Dependent Profibrotic Activity in Human Lung Myofibroblasts.
J Immunol
; 195(6): 2852-60, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26276873
3.
Increased constitutive αSMA and Smad2/3 expression in idiopathic pulmonary fibrosis myofibroblasts is KCa3.1-dependent.
Respir Res
; 15: 155, 2014 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25476248
4.
Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study.
Lancet Respir Med
; 11(1): 65-73, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35985358
5.
Human Lung Mast Cells Impair Corticosteroid Responsiveness in Human Airway Smooth Muscle Cells.
Front Allergy
; 2: 785100, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35387008
6.
TGFß1 induces resistance of human lung myofibroblasts to cell death via down-regulation of TRPA1 channels.
Br J Pharmacol
; 178(15): 2948-2962, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33786825
7.
Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors.
J Med Chem
; 64(14): 9960-9988, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34251197
8.
Ca2+ signalling in fibroblasts and the therapeutic potential of KCa3.1 channel blockers in fibrotic diseases.
Br J Pharmacol
; 177(5): 1003-1024, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31758702
9.
Tensin1 expression and function in chronic obstructive pulmonary disease.
Sci Rep
; 9(1): 18942, 2019 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31831813
10.
A model of human lung fibrogenesis for the assessment of anti-fibrotic strategies in idiopathic pulmonary fibrosis.
Sci Rep
; 8(1): 342, 2018 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29321510
11.
Human lung myofibroblast TGFß1-dependent Smad2/3 signalling is Ca(2+)-dependent and regulated by KCa3.1 K(+) channels.
Fibrogenesis Tissue Repair
; 8: 5, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25829947
12.
KCa3.1 K+ Channel Expression and Function in Human Bronchial Epithelial Cells.
PLoS One
; 10(12): e0145259, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26689552
13.
CADM1 is a key receptor mediating human mast cell adhesion to human lung fibroblasts and airway smooth muscle cells.
PLoS One
; 8(4): e61579, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23620770
14.
The K+ channel KCa3.1 as a novel target for idiopathic pulmonary fibrosis.
PLoS One
; 8(12): e85244, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24392001