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1.
Am J Dermatopathol ; 45(2): 81-85, 2023 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-36669069

RESUMO

ABSTRACT: An 84-year-old woman presented with a 3-month history of a papular rash on the trunk, abdomen, and back. Histopathological examination revealed atypical lymphoid deep and band-like dermal infiltrates with marked epidermotropism. Neoplastic cells expressed B-cell markers (CD20), and clonal immunoglobulin gene rearrangement was observed. A complete peripheral blood study revealed aberrant circulating villous lymphocytes with the expression of B-cell markers (CD20, CD22, and CD79a) and aberrant expression of CD5. A staging workup revealed discrete splenic enlargement and bone marrow and gastrointestinal tract involvement. Skin lesions regressed spontaneously several weeks after diagnosis. Throughout evolution, the patient developed scattered cutaneous nodules and generalized papulo-nodules showing either epidermotropic or nonepidermotropic atypical dermal lymphoid infiltrates. This case illustrates the observation of autoinvolutive and recurrent epidermotropic B-cell atypical cutaneous infiltrates as a characteristic feature of secondary cutaneous involvement in splenic marginal B-cell lymphoma. Previously reported cases of epidermotropic B-cell lymphoma have been reviewed. Concurrent and simultaneous observation of epidermotropic and nonepidermotropic lesions seems to indicate that epidermotropism is an important but nonconstant diagnostic feature of splenic marginal B-cell lymphoma.


Assuntos
Leucemia Linfocítica Crônica de Células B , Linfoma de Zona Marginal Tipo Células B , Dermatopatias , Neoplasias Cutâneas , Feminino , Humanos , Idoso de 80 Anos ou mais , Linfoma de Zona Marginal Tipo Células B/patologia , Pele/patologia , Neoplasias Cutâneas/patologia , Leucemia Linfocítica Crônica de Células B/patologia , Dermatopatias/patologia
6.
JAMA Dermatol ; 160(4): 474-476, 2024 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-38353959

RESUMO

This case report describes a 53-year-old man with multiple erythematous macules and papules diffusely distributed on the frontal area, cheeks, eyelids, nose, and supralabial skin.


Assuntos
Malformações Arteriovenosas , Capilares/anormalidades , Mancha Vinho do Porto , Humanos , Malformações Arteriovenosas/diagnóstico , Mancha Vinho do Porto/diagnóstico
8.
Int J STD AIDS ; 28(7): 732-734, 2017 06.
Artigo em Inglês | MEDLINE | ID: mdl-27881812

RESUMO

The typical finding in secondary syphilis stage is a generalized non-pruritic maculopapular eruption. We report a case of secondary syphilis in an HIV-infected patient presenting with pruritic crusted nodules showing numerous eosinophils on the histopathological examination.


Assuntos
Antibacterianos/uso terapêutico , Penicilina G Benzatina/administração & dosagem , Sífilis Cutânea/patologia , Sífilis/tratamento farmacológico , Treponema pallidum/isolamento & purificação , Exantema , Infecções por HIV/tratamento farmacológico , Humanos , Injeções Intramusculares , Masculino , Pessoa de Meia-Idade , Penicilina G Benzatina/uso terapêutico , Sífilis/patologia , Sífilis Cutânea/tratamento farmacológico , Resultado do Tratamento , Treponema pallidum/imunologia
9.
JAAD Case Rep ; 4(7): 622-624, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-30094300
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