Detalhe da pesquisa
1.
Lipophilic Statins Inhibit YAP Nuclear Localization, Coactivator Activity, and Migration in Response to Ligation of HLA Class I Molecules in Endothelial Cells: Role of YAP Multisite Phosphorylation.
J Immunol
; 210(8): 1134-1145, 2023 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36881871
2.
Human leukocyte antigen class I antibody-activated endothelium promotes CD206+ M2 macrophage polarization and MMP9 secretion through TLR4 signaling and P-selectin in a model of antibody-mediated rejection and allograft vasculopathy.
Am J Transplant
; 24(3): 406-418, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38379280
3.
Cross-Talk between HLA Class I and TLR4 Mediates P-Selectin Surface Expression and Monocyte Capture to Human Endothelial Cells.
J Immunol
; 209(7): 1359-1369, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36165200
4.
Statins inhibit protein kinase D (PKD) activation in intestinal cells and prevent PKD1-induced growth of murine enteroids.
Am J Physiol Cell Physiol
; 324(4): C807-C820, 2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36779664
5.
Lipophilic statins inhibit YAP coactivator transcriptional activity in HCC cells through Rho-mediated modulation of actin cytoskeleton.
Am J Physiol Gastrointest Liver Physiol
; 325(3): G239-G250, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37366601
6.
Metformin: review of epidemiology and mechanisms of action in pancreatic cancer.
Cancer Metastasis Rev
; 40(3): 865-878, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34142285
7.
Ligation of HLA Class I Molecules Induces YAP Activation through Src in Human Endothelial Cells.
J Immunol
; 205(7): 1953-1961, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32848033
8.
KRAS, YAP, and obesity in pancreatic cancer: A signaling network with multiple loops.
Semin Cancer Biol
; 54: 50-62, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29079305
9.
Metformin inhibition of colorectal cancer cell migration is associated with rebuilt adherens junctions and FAK downregulation.
J Cell Physiol
; 235(11): 8334-8344, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32239671
10.
HLA Class II-Triggered Signaling Cascades Cause Endothelial Cell Proliferation and Migration: Relevance to Antibody-Mediated Transplant Rejection.
J Immunol
; 200(7): 2372-2390, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29475988
11.
Protein kinase D1 inhibition interferes with mitosis progression.
J Cell Physiol
; 234(11): 20510-20519, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30997696
12.
Metformin alters the duodenal microbiome and decreases the incidence of pancreatic ductal adenocarcinoma promoted by diet-induced obesity.
Am J Physiol Gastrointest Liver Physiol
; 317(6): G763-G772, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31545922
13.
Protein kinase D1 (PKD1) phosphorylation on Ser203 by type I p21-activated kinase (PAK) regulates PKD1 localization.
J Biol Chem
; 292(23): 9523-9539, 2017 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28408623
14.
Outside-in HLA class I signaling regulates ICAM-1 clustering and endothelial cell-monocyte interactions via mTOR in transplant antibody-mediated rejection.
Am J Transplant
; 18(5): 1096-1109, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29045076
15.
Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice.
BMC Cancer
; 18(1): 797, 2018 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30086728
16.
Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD).
J Biol Chem
; 291(34): 17988-8005, 2016 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27369082
17.
Pancreatic cancer actionable genes in precision medicine and personalized surgery.
Surgeon
; 15(1): 24-29, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27374183
18.
Positive cross talk between protein kinase D and ß-catenin in intestinal epithelial cells: impact on ß-catenin nuclear localization and phosphorylation at Ser552.
Am J Physiol Cell Physiol
; 310(7): C542-57, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26739494
19.
Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1.
Am J Physiol Cell Physiol
; 309(10): C639-49, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26310818
20.
Intracellular Ca(2+) oscillations generated via the extracellular Ca(2+)-sensing receptor (CaSR) in response to extracellular Ca(2+) or L-phenylalanine: Impact of the highly conservative mutation Ser170Thr.
Biochem Biophys Res Commun
; 467(1): 1-6, 2015 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26431875